Head to Head
| NFL | 2018/10/21 17:00 | BUF Bills v IND Colts | W | 5-37 |
| NFL | 2017/12/10 18:00 | IND Colts v BUF Bills | L | 7-13 |
| NFL Preseason | 2016/08/13 23:00 | BUF Bills v IND Colts | W | 18-19 |
| NFL | 2015/09/13 17:00 | BUF Bills v IND Colts | L | 27-14 |
Home History
| NFL | 2019/01/12 21:35 | IND Colts v KC Chiefs | L | 13-31 |
| NFL | 2019/01/05 21:35 | IND Colts v HOU Texans | W | 21-7 |
| NFL | 2018/12/31 01:20 | IND Colts v TEN Titans | W | 33-17 |
| NFL | 2018/12/23 18:00 | NY Giants v IND Colts | W | 27-28 |
| NFL | 2018/12/16 18:00 | DAL Cowboys v IND Colts | W | 0-23 |
| NFL | 2018/12/09 18:00 | IND Colts v HOU Texans | W | 24-21 |
| NFL | 2018/12/02 18:00 | IND Colts v JAX Jaguars | L | 0-6 |
| NFL | 2018/11/25 21:25 | MIA Dolphins v IND Colts | W | 24-27 |
Away History
| NFL | 2018/12/30 18:00 | MIA Dolphins v BUF Bills | W | 17-42 |
| NFL | 2018/12/23 18:00 | BUF Bills v NE Patriots | L | 12-24 |
| NFL | 2018/12/16 18:00 | DET Lions v BUF Bills | W | 13-14 |
| NFL | 2018/12/09 18:00 | NY Jets v BUF Bills | L | 27-23 |
| NFL | 2018/12/02 18:00 | BUF Bills v MIA Dolphins | L | 17-21 |
| NFL | 2018/11/25 18:00 | JAX Jaguars v BUF Bills | W | 21-24 |
| NFL | 2018/11/11 18:00 | BUF Bills v NY Jets | W | 41-10 |
| NFL | 2018/11/04 18:00 | CHI Bears v BUF Bills | L | 41-9 |