Stadium: Robert W. Plaster Stadium Round: 1
Home Manager: Dave Steckel Away Manager: John Stiegelmeier
| NCAAF FCS | 2018/11/03 19:00 | Missouri St v South Dakota State | W | 7-59 |
| NCAAF | 2017/10/21 19:00 | Missouri St v South Dakota State | W | 30-62 |
| NCAAF | 2019/10/26 19:00 | North Dakota State v South Dakota State | L | 23-16 |
| NCAAF | 2019/10/19 17:00 | South Dakota State v Indiana State | W | 42-23 |
| NCAAF | 2019/10/12 22:00 | South Dakota State v Youngstown State | W | 38-28 |
| NCAAF | 2019/10/05 19:00 | SO Illinois v South Dakota State | W | 10-28 |
| NCAAF | 2019/09/21 23:00 | Southern Utah v South Dakota State | W | 7-43 |
| NCAAF | 2019/09/14 18:00 | Drake Bulldogs v South Dakota State | W | 10-38 |
| NCAAF | 2019/09/07 23:00 | South Dakota State v LIU Brooklyn | W | 38-3 |
| NCAAF | 2019/08/30 01:00 | South Dakota State v Minnesota | L | 21-28 |
| NCAAF | 2019/10/26 19:00 | Northern Iowa v Missouri St | L | 29-6 |
| NCAAF | 2019/10/19 19:30 | Missouri St v North Dakota State | L | 0-22 |
| NCAAF | 2019/10/12 19:00 | South Dakota v Missouri St | L | 45-10 |
| NCAAF | 2019/10/05 20:00 | Missouri St v Western Illinois | W | 37-31 |
| NCAAF | 2019/09/21 19:00 | Kennesaw State v Missouri St | L | 35-24 |
| NCAAF | 2019/09/15 00:00 | Missouri St v Tulane | L | 6-58 |
| NCAAF | 2019/08/30 01:00 | Missouri St v Northern Arizona | L | 23-37 |
| NCAAF FCS | 2018/11/17 22:00 | Missouri St v Northern Iowa | L | 0-37 |