Stadium: Dana J. Dykhouse Stadium Round: 1
Home Manager: John Stiegelmeier Away Manager: Brock Spack
| NCAAF | 2018/10/27 17:00 | Illinois State v South Dakota State | L | 28-38 |
| NCAAF | 2017/11/11 20:00 | South Dakota State v Illinois State | L | 27-24 |
| NCAAF | 2019/11/02 17:00 | Northern Iowa v Illinois State | L | 27-10 |
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | W | 7-24 |
| NCAAF | 2019/10/19 18:00 | Illinois State v Western Illinois | W | 28-14 |
| NCAAF | 2019/10/12 23:00 | Illinois State v SO Illinois | W | 21-7 |
| NCAAF | 2019/10/05 17:00 | North Dakota State v Illinois State | L | 37-3 |
| NCAAF | 2019/09/21 23:30 | Northern Arizona v Illinois State | W | 27-40 |
| NCAAF | 2019/09/14 19:00 | Illinois State v Eastern Illinois | W | 21-3 |
| NCAAF | 2019/09/07 23:30 | Morehead State v Illinois State | W | 14-42 |
| NCAAF | 2019/11/02 19:00 | South Dakota State v Missouri St | W | 35-14 |
| NCAAF | 2019/10/26 19:00 | North Dakota State v South Dakota State | L | 23-16 |
| NCAAF | 2019/10/19 17:00 | South Dakota State v Indiana State | W | 42-23 |
| NCAAF | 2019/10/12 22:00 | South Dakota State v Youngstown State | W | 38-28 |
| NCAAF | 2019/10/05 19:00 | SO Illinois v South Dakota State | W | 10-28 |
| NCAAF | 2019/09/21 23:00 | Southern Utah v South Dakota State | W | 7-43 |
| NCAAF | 2019/09/14 18:00 | Drake Bulldogs v South Dakota State | W | 10-38 |
| NCAAF | 2019/09/07 23:00 | South Dakota State v LIU Brooklyn | W | 38-3 |