Illinois St 21-7 Southern Illinois 2019-10-12 23:00
Stadium: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Brock Spack
Head to Head
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | W | 3-51 |
| NCAAF | 2017/10/14 19:00 | SO Illinois v Illinois State | L | 42-7 |
Home History
| NCAAF | 2019/10/05 17:00 | North Dakota State v Illinois State | L | 37-3 |
| NCAAF | 2019/09/21 23:30 | Northern Arizona v Illinois State | W | 27-40 |
| NCAAF | 2019/09/14 19:00 | Illinois State v Eastern Illinois | W | 21-3 |
| NCAAF | 2019/09/07 23:30 | Morehead State v Illinois State | W | 14-42 |
| NCAAF | 2019/08/31 23:00 | Illinois State v Northern Illinois | L | 10-24 |
| NCAAF FCS | 2018/11/17 18:00 | Youngstown State v Illinois State | W | 28-35 |
| NCAAF FCS | 2018/11/10 18:00 | Illinois State v Indiana State | L | 23-28 |
| NCAAF FCS | 2018/11/03 18:00 | Illinois State v Northern Iowa | L | 16-26 |
Away History
| NCAAF | 2019/10/05 19:00 | SO Illinois v South Dakota State | L | 10-28 |
| NCAAF | 2019/09/21 23:00 | SO Illinois v Arkansas State | L | 28-41 |
| NCAAF | 2019/09/14 23:00 | Tennessee Martin v SO Illinois | W | 14-28 |
| NCAAF | 2019/09/07 19:30 | SO Illinois v Massachusetts | W | 45-20 |
| NCAAF | 2019/08/29 23:30 | SO Illinois v SE Missouri St | L | 26-44 |
| NCAAF FCS | 2018/11/17 20:30 | SO Illinois v North Dakota State | L | 17-65 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | L | 57-38 |
| NCAAF FCS | 2018/11/03 18:00 | Western Illinois v SO Illinois | L | 34-31 |