Stadium: Robert W. Plaster Stadium Round: 1
Home Manager: Dave Steckel Away Manager: Curt Mallory
| NCAAF | 2018/10/13 18:00 | Missouri St v Indiana State | L | 29-26 |
| NCAAF | 2017/10/28 19:00 | Missouri St v Indiana State | L | 59-20 |
| NCAAF | 2019/11/16 18:00 | Youngstown State v Indiana State | W | 17-24 |
| NCAAF | 2019/11/09 22:00 | Indiana State v Northern Iowa | L | 9-17 |
| NCAAF | 2019/11/02 17:00 | SO Illinois v Indiana State | L | 23-14 |
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | L | 7-24 |
| NCAAF | 2019/10/19 17:00 | South Dakota State v Indiana State | L | 42-23 |
| NCAAF | 2019/10/12 17:00 | Western Illinois v Indiana State | W | 10-20 |
| NCAAF | 2019/10/05 19:00 | Indiana State v South Dakota | L | 0-38 |
| NCAAF | 2019/09/21 17:00 | Eastern Illinois v Indiana State | W | 6-16 |
| NCAAF | 2019/11/16 18:00 | Missouri St v Illinois State | L | 12-17 |
| NCAAF | 2019/11/09 20:00 | Missouri St v SO Illinois | L | 14-37 |
| NCAAF | 2019/11/02 19:00 | South Dakota State v Missouri St | L | 35-14 |
| NCAAF | 2019/10/26 19:00 | Northern Iowa v Missouri St | L | 29-6 |
| NCAAF | 2019/10/19 19:30 | Missouri St v North Dakota State | L | 0-22 |
| NCAAF | 2019/10/12 19:00 | South Dakota v Missouri St | L | 45-10 |
| NCAAF | 2019/10/05 20:00 | Missouri St v Western Illinois | W | 37-31 |
| NCAAF | 2019/09/21 19:00 | Kennesaw State v Missouri St | L | 35-24 |