Stadium: Hancock Stadium Round: 1
Home Manager: Brock Spack Away Manager: Dave Steckel
| NCAAF | 2018/09/29 19:00 | Illinois State v Missouri St | W | 21-24 |
| NCAAF | 2017/09/23 19:00 | Missouri St v Illinois State | L | 9-34 |
| NCAAF | 2019/11/09 20:00 | Missouri St v SO Illinois | L | 14-37 |
| NCAAF | 2019/11/02 19:00 | South Dakota State v Missouri St | L | 35-14 |
| NCAAF | 2019/10/26 19:00 | Northern Iowa v Missouri St | L | 29-6 |
| NCAAF | 2019/10/19 19:30 | Missouri St v North Dakota State | L | 0-22 |
| NCAAF | 2019/10/12 19:00 | South Dakota v Missouri St | L | 45-10 |
| NCAAF | 2019/10/05 20:00 | Missouri St v Western Illinois | W | 37-31 |
| NCAAF | 2019/09/21 19:00 | Kennesaw State v Missouri St | L | 35-24 |
| NCAAF | 2019/09/15 00:00 | Missouri St v Tulane | L | 6-58 |
| NCAAF | 2019/11/09 20:00 | Illinois State v South Dakota State | W | 27-18 |
| NCAAF | 2019/11/02 17:00 | Northern Iowa v Illinois State | L | 27-10 |
| NCAAF | 2019/10/26 19:00 | Indiana State v Illinois State | W | 7-24 |
| NCAAF | 2019/10/19 18:00 | Illinois State v Western Illinois | W | 28-14 |
| NCAAF | 2019/10/12 23:00 | Illinois State v SO Illinois | W | 21-7 |
| NCAAF | 2019/10/05 17:00 | North Dakota State v Illinois State | L | 37-3 |
| NCAAF | 2019/09/21 23:30 | Northern Arizona v Illinois State | W | 27-40 |
| NCAAF | 2019/09/14 19:00 | Illinois State v Eastern Illinois | W | 21-3 |