Southern Illinois 10-28 South Dakota St 2019-10-05 19:00
Stadium: Dana J. Dykhouse Stadium Round: 1
Home Manager: John Stiegelmeier Away Manager: Nick Hill
Head to Head
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | L | 57-38 |
| NCAAF | 2017/10/07 23:00 | South Dakota State v SO Illinois | L | 49-14 |
Home History
| NCAAF | 2019/09/21 23:00 | SO Illinois v Arkansas State | L | 28-41 |
| NCAAF | 2019/09/14 23:00 | Tennessee Martin v SO Illinois | W | 14-28 |
| NCAAF | 2019/09/07 19:30 | SO Illinois v Massachusetts | W | 45-20 |
| NCAAF | 2019/08/29 23:30 | SO Illinois v SE Missouri St | L | 26-44 |
| NCAAF FCS | 2018/11/17 20:30 | SO Illinois v North Dakota State | L | 17-65 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | L | 57-38 |
| NCAAF FCS | 2018/11/03 18:00 | Western Illinois v SO Illinois | L | 34-31 |
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | W | 35-49 |
Away History
| NCAAF | 2019/09/21 23:00 | Southern Utah v South Dakota State | W | 7-43 |
| NCAAF | 2019/09/14 18:00 | Drake Bulldogs v South Dakota State | W | 10-38 |
| NCAAF | 2019/09/07 23:00 | South Dakota State v LIU Brooklyn | W | 38-3 |
| NCAAF | 2019/08/30 01:00 | South Dakota State v Minnesota | L | 21-28 |
| NCAAF FCS | 2018/12/15 01:00 | South Dakota State v North Dakota State | L | 21-44 |
| NCAAF | 2018/12/08 19:00 | Kennesaw State v South Dakota State | W | 17-27 |
| NCAAF FCS | 2018/12/01 20:00 | Duquesne v South Dakota State | W | 6-51 |
| NCAAF FCS | 2018/11/17 20:00 | South Dakota v South Dakota State | W | 27-49 |