Head to Head
| NCAAF | 2008/10/25 12:00 | Louisville v South Florida | L | 24-20 |
| NCAAF | 2007/11/17 12:00 | South Florida v Louisville | W | 55-17 |
| NCAAF | 2006/11/18 12:00 | Louisville v South Florida | L | 31-8 |
| NCAAF | 2005/09/24 12:00 | South Florida v Louisville | W | 45-14 |
| NCAAF | 2004/10/22 12:00 | Louisville v South Florida | L | 41-9 |
| NCAAF | 2003/10/04 12:00 | South Florida v Louisville | W | 31-28 |
Home History
| NCAAF | 2009/11/12 12:00 | Rutgers v South Florida | L | 31-0 |
| NCAAF | 2009/10/30 12:00 | South Florida v West Virginia | W | 30-19 |
| NCAAF | 2009/10/24 12:00 | Pittsburgh v South Florida | L | 41-14 |
| NCAAF | 2009/10/15 12:00 | South Florida v Cincinnati | L | 17-34 |
| NCAAF | 2009/09/26 12:00 | Florida State v South Florida | W | 7-17 |
| NCAAF | 2009/09/19 12:00 | South Florida v Charleston Southern | W | 59-0 |
| NCAAF | 2009/09/12 12:00 | Western Kentucky v South Florida | W | 13-35 |
| NCAAF | 2009/09/05 12:00 | South Florida v Wofford | W | 40-7 |
Away History
| NCAAF | 2009/11/14 12:00 | Louisville v Syracuse | W | 10-9 |
| NCAAF | 2009/11/07 12:00 | West Virginia v Louisville | L | 17-9 |
| NCAAF | 2009/10/31 12:00 | Louisville v Arkansas State | W | 21-13 |
| NCAAF | 2009/10/24 12:00 | Cincinnati v Louisville | L | 41-10 |
| NCAAF | 2009/10/17 12:00 | Connecticut v Louisville | L | 38-25 |
| NCAAF | 2009/10/10 12:00 | Louisville v Southern Mississippi | W | 25-23 |
| NCAAF | 2009/09/26 12:00 | Utah v Louisville | L | 30-14 |
| NCAAF | 2009/09/19 12:00 | Kentucky v Louisville | L | 31-27 |