Head to Head
| NCAAF | 2008/10/25 12:00 | Louisville v South Florida | L | 24-20 |
| NCAAF | 2007/11/17 12:00 | South Florida v Louisville | W | 55-17 |
| NCAAF | 2006/11/18 12:00 | Louisville v South Florida | L | 31-8 |
| NCAAF | 2005/09/24 12:00 | South Florida v Louisville | W | 45-14 |
| NCAAF | 2004/10/22 12:00 | Louisville v South Florida | L | 41-9 |
| NCAAF | 2003/10/04 12:00 | South Florida v Louisville | W | 31-28 |