[13] Southampton 2-5 Tottenham [14] 2020-09-20 11:00
Stadium: St. Mary's Stadium Round: 2
Referee: David Coote Home Manager: Ralph Hasenhuttl Away Manager: Jose Mourinho
Head to Head
| England FA Cup | 2020/02/05 19:45 | Tottenham v Southampton | L | 3-2 |
| England FA Cup | 2020/01/25 15:00 | Southampton v Tottenham | D | 1-1 |
| England Premier League | 2020/01/01 15:00 | Southampton v Tottenham | W | 1-0 |
| England Premier League | 2019/09/28 14:00 | Tottenham v Southampton | L | 2-1 |
| England Premier League | 2019/03/09 15:00 | Southampton v Tottenham | W | 2-1 |
| England Premier League | 2018/12/05 20:00 | Tottenham v Southampton | L | 3-1 |
| England Premier League | 2018/01/21 16:00 | Southampton v Tottenham | D | 1-1 |
| England Premier League | 2017/12/26 12:30 | Tottenham v Southampton | L | 5-2 |
Home History
| England EFL Cup | 2020/09/16 18:45 | Southampton v Brentford | L | 0-2 |
| England Premier League | 2020/09/12 14:00 | Crystal Palace v Southampton | L | 1-0 |
| England Premier League | 2020/07/26 15:00 | Southampton v Sheff Utd | W | 3-1 |
| England Premier League | 2020/07/19 13:00 | Bournemouth v Southampton | W | 0-2 |
| England Premier League | 2020/07/16 19:15 | Southampton v Brighton | D | 1-1 |
| England Premier League | 2020/07/13 19:00 | Man Utd v Southampton | D | 2-2 |
| England Premier League | 2020/07/09 17:00 | Everton v Southampton | D | 1-1 |
| England Premier League | 2020/07/05 18:00 | Southampton v Man City | W | 1-0 |
Away History
| UEFA Europa League Qualifying | 2020/09/17 16:00 | Lokomotiv Plovdiv v Tottenham | W | 1-2 |
| England Premier League | 2020/09/13 15:30 | Tottenham v Everton | L | 0-1 |
| Europe Friendlies | 2020/09/05 14:00 | Watford v Tottenham | L | 2-1 |
| Elite Club Friendlies | 2020/08/29 14:00 | Tottenham v Birmingham | W | 1-0 |
| Elite Club Friendlies | 2020/08/28 14:30 | Tottenham v Reading | W | 4-1 |
| Elite Club Friendlies | 2020/08/22 14:00 | Tottenham v Ipswich | W | 3-0 |
| England Premier League | 2020/07/26 15:00 | Crystal Palace v Tottenham | D | 1-1 |
| England Premier League | 2020/07/19 15:00 | Tottenham v Leicester | W | 3-0 |