[50] Kansas State 0-45 Iowa State [25] 2020-11-21 21:00
Stadium: Jack Trice Stadium Round: 1
Head to Head
| NCAAF | 2019/12/01 00:00 | Iowa State v Kansas State | W | 17-27 |
| NCAAF | 2018/11/25 00:00 | Kansas State v Iowa State | L | 38-42 |
| NCAAF | 2017/11/25 20:30 | Iowa State v Kansas State | W | 19-20 |
| NCAAF | 2016/10/29 16:00 | Kansas State v Iowa State | W | 31-26 |
| NCAAF | 2015/11/21 17:00 | Kansas State v Iowa State | W | 38-35 |
| NCAAF | 2014/09/06 16:00 | Iowa State v Kansas State | W | 28-32 |
| NCAAF | 2012/10/13 12:00 | Iowa State v Kansas State | W | 21-27 |
| NCAAF | 2011/12/03 12:00 | Kansas State v Iowa State | W | 30-23 |
Home History
| NCAAF | 2020/11/07 21:00 | Oklahoma State v Kansas State | L | 20-18 |
| NCAAF | 2020/10/31 16:00 | Kansas State v West Virginia | L | 10-37 |
| NCAAF | 2020/10/24 16:00 | Kansas v Kansas State | W | 14-55 |
| NCAAF | 2020/10/10 20:00 | Kansas State v TCU | W | 21-14 |
| NCAAF | 2020/10/03 19:30 | Texas Tech v Kansas State | W | 21-31 |
| NCAAF | 2020/09/26 16:00 | Kansas State v Oklahoma | W | 38-35 |
| NCAAF | 2020/09/12 16:00 | Arkansas State v Kansas State | L | 35-31 |
| NCAAF | 2019/12/31 20:45 | Kansas State v Navy | L | 17-20 |
Away History
| NCAAF | 2020/11/08 00:00 | Baylor v Iowa State | W | 31-38 |
| NCAAF | 2020/10/31 16:00 | Iowa State v Kansas | W | 52-22 |
| NCAAF | 2020/10/24 19:30 | Iowa State v Oklahoma State | L | 21-24 |
| NCAAF | 2020/10/10 19:30 | Texas Tech v Iowa State | W | 15-31 |
| NCAAF | 2020/10/03 23:30 | Oklahoma v Iowa State | W | 30-37 |
| NCAAF | 2020/09/26 17:30 | Iowa State v TCU | W | 37-34 |
| NCAAF | 2020/09/12 16:00 | Lafayette v Iowa State | L | 31-14 |
| NCAAF | 2019/12/28 17:00 | Iowa State v Notre Dame | L | 9-33 |