[117] Michigan State 27-24 Michigan [64] 2020-10-31 16:00
Stadium: Michigan Stadium Round: 1
Head to Head
| NCAAF | 2019/11/16 17:00 | Michigan State v Michigan | L | 10-44 |
| NCAAF | 2018/10/20 16:00 | Michigan v Michigan State | L | 21-7 |
| NCAAF | 2017/10/07 23:30 | Michigan State v Michigan | W | 14-10 |
| NCAAF | 2016/10/29 16:00 | Michigan v Michigan State | L | 32-23 |
| NCAAF | 2015/10/17 19:30 | Michigan v Michigan State | W | 23-27 |
| NCAAF | 2014/10/25 19:30 | Michigan State v Michigan | W | 35-11 |
| NCAAF | 2012/10/20 12:00 | Michigan v Michigan State | L | 12-10 |
| NCAAF | 2011/10/15 12:00 | Michigan State v Michigan | W | 28-14 |
Home History
| NCAAF | 2020/10/24 16:00 | Rutgers v Michigan State | L | 38-27 |
| NCAAF | 2019/12/27 20:20 | Michigan State v Wake Forest | W | 27-21 |
| NCAAF | 2019/11/30 20:30 | Maryland v Michigan State | W | 16-19 |
| NCAAF | 2019/11/23 17:00 | Michigan State v Rutgers | W | 27-0 |
| NCAAF | 2019/11/16 17:00 | Michigan State v Michigan | L | 10-44 |
| NCAAF | 2019/11/09 20:30 | Illinois v Michigan State | L | 37-34 |
| NCAAF | 2019/10/26 19:30 | Penn State v Michigan State | L | 28-7 |
| NCAAF | 2019/10/12 19:30 | Michigan State v Wisconsin | L | 0-38 |
Away History
| NCAAF | 2020/10/24 23:30 | Michigan v Minnesota | W | 49-24 |
| NCAAF | 2020/01/01 18:00 | Michigan v Alabama | L | 16-35 |
| NCAAF | 2019/11/30 17:00 | Ohio State v Michigan | L | 56-27 |
| NCAAF | 2019/11/23 20:30 | Michigan v Indiana | W | 39-14 |
| NCAAF | 2019/11/16 17:00 | Michigan State v Michigan | W | 10-44 |
| NCAAF | 2019/11/02 16:00 | Michigan v Maryland | W | 38-7 |
| NCAAF | 2019/10/26 23:30 | Notre Dame v Michigan | W | 14-45 |
| NCAAF | 2019/10/19 23:30 | Michigan v Penn State | L | 21-28 |