[2] River Plate 1-2 San Lorenzo [5] 2021-04-25 21:00
Stadium: Estadio Monumental Antonio Vespucio Liberti Round: 11
Referee: Fernando Echenique Home Manager: Marcelo Gallardo Away Manager: Diego Dabove
Head to Head
| Argentina Superliga | 2019/12/09 00:45 | River Plate v San Lorenzo | L | 0-1 |
| Argentina Superliga | 2018/09/01 23:00 | San Lorenzo v River Plate | D | 1-1 |
| Argentina Superliga | 2018/05/15 00:15 | River Plate v San Lorenzo | W | 2-0 |
| Argentina Superliga | 2017/06/04 17:00 | San Lorenzo v River Plate | L | 2-1 |
| Argentina Liga Profesional | 2016/05/07 20:45 | San Lorenzo v River Plate | L | 2-1 |
| Argentina Torneo De Verano | 2016/01/27 01:10 | River Plate v San Lorenzo | W | 3-2 |
| Argentina Liga Profesional | 2015/04/05 19:00 | River Plate v San Lorenzo | W | 1-0 |
| Recopa Sudamericana | 2015/02/12 00:00 | San Lorenzo v River Plate | W | 0-1 |
Home History
| Copa Libertadores | 2021/04/22 22:00 | Fluminense v River Plate | D | 1-1 |
| Argentina Copa de la Liga Profesional | 2021/04/17 00:30 | Central Cordoba v River Plate | W | 0-5 |
| Argentina Copa de la Liga Profesional | 2021/04/12 00:00 | River Plate v Colon | W | 3-2 |
| Argentina Cup | 2021/04/07 23:30 | Atlético Tucumán v River Plate | W | 1-2 |
| Argentina Copa de la Liga Profesional | 2021/04/04 00:00 | Arsenal de Sarandi v River Plate | D | 0-0 |
| Argentina Copa de la Liga Profesional | 2021/03/28 21:30 | River Plate v Racing Club | D | 0-0 |
| Argentina Copa de la Liga Profesional | 2021/03/21 00:00 | Godoy Cruz v River Plate | W | 1-6 |
| Argentina Copa de la Liga Profesional | 2021/03/14 21:00 | Boca Juniors v River Plate | D | 1-1 |
Away History
| Copa Sudamericana | 2021/04/21 22:15 | San Lorenzo v Huachipato | L | 0-1 |
| Argentina Copa de la Liga Profesional | 2021/04/17 18:45 | San Lorenzo v Argentinos Jrs | D | 1-1 |
| Copa Libertadores Qualification | 2021/04/14 00:30 | Santos v San Lorenzo | D | 2-2 |
| Argentina Copa de la Liga Profesional | 2021/04/10 00:00 | Platense v San Lorenzo | W | 2-4 |
| Copa Libertadores Qualification | 2021/04/07 00:30 | San Lorenzo v Santos | L | 1-3 |
| Argentina Copa de la Liga Profesional | 2021/04/02 22:00 | San Lorenzo v Rosario Central | W | 2-0 |
| Argentina Copa de la Liga Profesional | 2021/03/29 22:00 | Estudiantes LP v San Lorenzo | W | 0-2 |
| Argentina Cup | 2021/03/25 22:10 | San Lorenzo v Defensa y Justicia | L | 0-2 |