[4] Cerro Porteno 2-2 Guairena FC [9] 2021-02-21 21:30
Stadium: General Pablo Rojas Round: 4
Referee: Alipio Colman Home Manager: Francisco Arce Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2020/11/07 21:15 | Guairena FC v Cerro Porteno | D | 1-1 |
| Paraguay Division Profesional | 2020/08/26 21:00 | Guairena FC v Cerro Porteno | W | 1-2 |
| Paraguay Division Profesional | 2020/02/15 22:15 | Cerro Porteno v Guairena FC | D | 2-2 |
Home History
| Paraguay Division Profesional | 2021/02/15 23:45 | Libertad Asuncion v Cerro Porteno | L | 2-1 |
| Paraguay Division Profesional | 2021/02/10 21:30 | Cerro Porteno v Sportivo Luqueno | W | 1-0 |
| Paraguay Division Profesional | 2021/02/06 23:45 | Sol de America v Cerro Porteno | W | 1-3 |
| Paraguay Division Profesional | 2020/12/23 00:00 | Cerro Porteno v Olimpia Asuncion | L | 2-5 |
| Paraguay Division Profesional | 2020/12/18 22:30 | 12 de Octubre v Cerro Porteno | L | 2-1 |
| Paraguay Division Profesional | 2020/12/13 23:30 | Cerro Porteno v Sportivo San Lorenzo | D | 1-1 |
| Paraguay Division Profesional | 2020/12/07 23:00 | Nacional Asuncion v Cerro Porteno | L | 4-3 |
| Paraguay Division Profesional | 2020/12/03 22:30 | Cerro Porteno v Olimpia Asuncion | W | 1-0 |
Away History
| Paraguay Division Profesional | 2021/02/14 23:45 | Olimpia Asuncion v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2021/02/05 21:30 | Sportivo Luqueno v Guairena FC | L | 3-1 |
| Paraguay Division Profesional | 2020/12/28 00:00 | Guairena FC v Guarani Asuncion | L | 0-1 |
| Paraguay Division Profesional | 2020/12/23 21:30 | 12 de Octubre v Guairena FC | W | 1-2 |
| Paraguay Division Profesional | 2020/12/19 22:30 | Guarani Asuncion v Guairena FC | L | 1-0 |
| Paraguay Division Profesional | 2020/12/11 21:30 | Guairena FC v Sportivo Luqueno | W | 1-0 |
| Paraguay Division Profesional | 2020/12/06 13:00 | 12 de Octubre v Guairena FC | L | 3-0 |
| Paraguay Division Profesional | 2020/11/27 23:30 | Guairena FC v Sportivo San Lorenzo | D | 2-2 |