Vanderbilt 28-6 Middle Tennessee St. 2017-09-03 00:00
Stadium: Johnny "Red" Floyd Stadium Round: 1
Head to Head
| NCAAF | 2016/09/10 20:00 | Vanderbilt v Middle Tennessee St. | W | 47-24 |
| NCAAF | 2015/10/03 23:00 | Middle Tennessee St. v Vanderbilt | W | 13-17 |
| NCAAF | 2005/10/01 12:00 | Vanderbilt v Middle Tennessee St. | L | 15-17 |
| NCAAF | 2002/10/12 12:00 | Vanderbilt v Middle Tennessee St. | L | 20-21 |
| NCAAF | 2001/08/30 12:00 | Vanderbilt v Middle Tennessee St. | L | 28-37 |
Home History
| NCAAF | 2016/12/26 22:00 | Vanderbilt v NC State | L | 17-41 |
| NCAAF | 2016/11/27 00:30 | Tennessee v Vanderbilt | W | 34-45 |
| NCAAF | 2016/11/20 01:00 | Mississippi v Vanderbilt | W | 17-38 |
| NCAAF | 2016/11/12 20:30 | Vanderbilt v Missouri | L | 17-26 |
| NCAAF | 2016/11/05 16:00 | Vanderbilt v Auburn | L | 16-23 |
| NCAAF | 2016/10/22 23:30 | Tennessee State v Vanderbilt | W | 17-35 |
| NCAAF | 2016/10/15 16:00 | Vanderbilt v Georgia | W | 17-16 |
| NCAAF | 2016/10/08 20:00 | Vanderbilt v Kentucky | L | 13-20 |
Away History
| NCAAF | 2016/12/25 01:00 | Middle Tennessee St. v Hawaii | L | 35-52 |
| NCAAF | 2016/11/26 22:30 | Florida Atlantic v Middle Tennessee St. | W | 56-77 |
| NCAAF | 2016/11/19 19:00 | Middle Tennessee St. v Charlotte | W | 38-31 |
| NCAAF | 2016/11/13 00:00 | Middle Tennessee St. v Marshall | L | 17-42 |
| NCAAF | 2016/11/05 18:30 | Texas-San Antonio v Middle Tennessee St. | L | 45-25 |
| NCAAF | 2016/10/29 23:00 | Middle Tennessee St. v Florida Intl | W | 42-35 |
| NCAAF | 2016/10/22 20:00 | Middle Tennessee St. v Missouri | W | 51-45 |
| NCAAF | 2016/10/15 18:30 | Western Kentucky v Middle Tennessee St. | L | 44-43 |