Vanderbilt 28-6 Middle Tennessee St. 2017-09-03 00:00
Stadium: Johnny "Red" Floyd Stadium Round: 1
Head to Head
| NCAAF | 2016/09/10 20:00 | Vanderbilt v Middle Tennessee St. | W | 47-24 |
| NCAAF | 2015/10/03 23:00 | Middle Tennessee St. v Vanderbilt | W | 13-17 |
| NCAAF | 2005/10/01 12:00 | Vanderbilt v Middle Tennessee St. | L | 15-17 |
| NCAAF | 2002/10/12 12:00 | Vanderbilt v Middle Tennessee St. | L | 20-21 |
| NCAAF | 2001/08/30 12:00 | Vanderbilt v Middle Tennessee St. | L | 28-37 |