Stadium: Madison Square Garden Round: 3
Home Manager: Dan Hurley Away Manager: Dave Leitao
| NCAAB | 2021/01/11 23:00 | Connecticut v DePaul | L | 60-53 |
| NCAAB | 2020/12/31 02:00 | DePaul v Connecticut | L | 61-82 |
| NCAAB | 2012/03/06 12:00 | Connecticut v DePaul | L | 81-67 |
| NCAAB | 2012/02/15 12:00 | Connecticut v DePaul | L | 80-54 |
| NCAAB | 2011/03/08 12:00 | Connecticut v DePaul | L | 97-71 |
| NCAAB | 2011/01/15 12:00 | DePaul v Connecticut | L | 62-82 |
| NCAAB | 2010/02/06 12:00 | Connecticut v DePaul | L | 64-57 |
| NCAAB | 2009/01/28 12:00 | DePaul v Connecticut | L | 49-71 |
| NCAAB | 2021/03/11 02:00 | DePaul v Providence | W | 70-62 |
| NCAAB | 2021/03/03 02:00 | Marquette v DePaul | L | 77-71 |
| NCAAB | 2021/02/27 17:00 | Georgetown v DePaul | L | 68-60 |
| NCAAB | 2021/02/25 02:00 | DePaul v Creighton | L | 53-77 |
| NCAAB | 2021/02/21 00:30 | DePaul v St Johns | W | 88-83 |
| NCAAB | 2021/02/18 01:30 | DePaul v Seton Hall | L | 52-60 |
| NCAAB | 2021/02/14 01:00 | Providence v DePaul | L | 57-47 |
| NCAAB | 2021/02/06 17:00 | DePaul v Butler | L | 58-68 |
| NCAAB | 2021/03/06 17:00 | Georgetown v Connecticut | W | 82-98 |
| NCAAB | 2021/03/03 23:30 | Connecticut v Seton Hall | W | 69-58 |
| NCAAB | 2021/02/27 19:30 | Marquette v Connecticut | W | 62-80 |
| NCAAB | 2021/02/24 02:00 | Connecticut v Georgetown | W | 70-57 |
| NCAAB | 2021/02/20 18:00 | Connecticut v Villanova | L | 60-68 |
| NCAAB | 2021/02/16 23:30 | Providence v Connecticut | W | 61-73 |
| NCAAB | 2021/02/13 17:00 | Connecticut v Xavier | W | 80-72 |
| NCAAB | 2021/02/10 21:00 | Connecticut v Providence | L | 59-70 |