Stadium: Madison Square Garden Round: 3
Home Manager: Dan Hurley Away Manager: Dave Leitao
| NCAAB | 2021/01/11 23:00 | Connecticut v DePaul | L | 60-53 |
| NCAAB | 2020/12/31 02:00 | DePaul v Connecticut | L | 61-82 |
| NCAAB | 2012/03/06 12:00 | Connecticut v DePaul | L | 81-67 |
| NCAAB | 2012/02/15 12:00 | Connecticut v DePaul | L | 80-54 |
| NCAAB | 2011/03/08 12:00 | Connecticut v DePaul | L | 97-71 |
| NCAAB | 2011/01/15 12:00 | DePaul v Connecticut | L | 62-82 |
| NCAAB | 2010/02/06 12:00 | Connecticut v DePaul | L | 64-57 |
| NCAAB | 2009/01/28 12:00 | DePaul v Connecticut | L | 49-71 |
| NCAAB | 2008/02/19 12:00 | Connecticut v DePaul | L | 65-60 |
| NCAAB | 2007/01/31 12:00 | DePaul v Connecticut | W | 66-58 |
| NCAAB | 2004/03/20 12:00 | Connecticut v DePaul | L | 72-55 |