South Dakota State 44-3 Southern Illinois 2021-03-20 17:00
Stadium: Saluki Stadium Round: 1
Head to Head
| NCAAF | 2019/10/05 19:00 | SO Illinois v South Dakota State | W | 10-28 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | W | 57-38 |
| NCAAF | 2017/10/07 23:00 | South Dakota State v SO Illinois | W | 49-14 |
Home History
| NCAAF | 2021/03/13 20:00 | Youngstown State v South Dakota State | W | 17-19 |
| NCAAF | 2021/03/06 20:00 | Western Illinois v South Dakota State | W | 10-45 |
| NCAAF | 2021/02/27 18:00 | South Dakota State v North Dakota | L | 17-28 |
| NCAAF | 2021/02/20 01:00 | South Dakota State v Northern Iowa | W | 24-20 |
| NCAAF | 2019/12/07 19:00 | Northern Iowa v South Dakota State | L | 13-10 |
| NCAAF | 2019/11/23 20:00 | South Dakota State v South Dakota | L | 21-24 |
| NCAAF | 2019/11/16 20:00 | Northern Iowa v South Dakota State | W | 7-38 |
| NCAAF | 2019/11/09 20:00 | Illinois State v South Dakota State | L | 27-18 |
Away History
| NCAAF | 2021/03/13 18:00 | Northern Iowa v SO Illinois | W | 16-17 |
| NCAAF | 2021/03/06 17:00 | SO Illinois v Youngstown State | W | 30-22 |
| NCAAF | 2021/02/27 18:00 | North Dakota State v SO Illinois | W | 14-38 |
| NCAAF | 2021/02/20 18:00 | SO Illinois v North Dakota | L | 21-44 |
| NCAAF | 2020/10/30 23:00 | SE Missouri St v SO Illinois | W | 17-20 |
| NCAAF | 2019/11/23 20:00 | North Dakota State v SO Illinois | L | 21-7 |
| NCAAF | 2019/11/16 19:00 | SO Illinois v Western Illinois | W | 45-21 |
| NCAAF | 2019/11/09 20:00 | Missouri St v SO Illinois | W | 14-37 |