[9] Harlequins 50-21 Northampton [10] 2017-12-30 16:00
Stadium: London Round: 12
Referee: JP Doyle Home Manager: Mark Mapletoft Away Manager: Alan Dickens
Head to Head
| Premiership Rugby | 2017/09/30 14:00 | Northampton v Harlequins | L | 30-22 |
| Premiership Rugby | 2017/05/06 15:00 | Northampton v Harlequins | L | 22-20 |
| Premiership Rugby | 2016/10/08 14:00 | Harlequins v Northampton | W | 20-9 |
| Premiership Rugby | 2016/03/27 14:15 | Northampton v Harlequins | L | 29-23 |
| Premiership Rugby | 2016/02/06 14:00 | Harlequins v Northampton | L | 23-27 |
| Premiership Rugby | 2015/02/27 19:45 | Northampton v Harlequins | L | 17-13 |
| Premiership Rugby | 2014/12/27 16:30 | Harlequins v Northampton | L | 25-30 |
| European Rugby Challenge Cup | 2014/04/25 19:00 | Northampton v Harlequins | L | 18-10 |
Home History
| Premiership Rugby | 2017/12/23 15:00 | Newcastle Falcons v Harlequins | L | 11-10 |
| Premiership Rugby Shield | 2017/12/18 19:30 | Harlequins v Bristol United | W | 73-14 |
| European Rugby Champions Cup | 2017/12/15 19:45 | Ulster v Harlequins | L | 52-24 |
| European Rugby Champions Cup | 2017/12/10 13:00 | Harlequins v Ulster | L | 5-17 |
| Premiership Rugby | 2017/12/03 15:00 | Harlequins v Saracens | W | 20-19 |
| Premiership Rugby | 2017/11/25 12:45 | Bath v Harlequins | L | 38-14 |
| Premiership Rugby | 2017/11/19 15:00 | Exeter Chiefs v Harlequins | L | 31-17 |
| LV Cup | 2017/11/12 15:00 | Harlequins v Worcester Warriors | W | 45-37 |
Away History
| Premiership Rugby | 2017/12/23 15:00 | Northampton v Exeter Chiefs | L | 14-35 |
| European Rugby Champions Cup | 2017/12/17 15:15 | Ospreys v Northampton | L | 32-15 |
| European Rugby Champions Cup | 2017/12/09 17:30 | Northampton v Ospreys | L | 32-43 |
| Premiership Rugby | 2017/12/01 19:45 | Northampton v Newcastle Falcons | L | 22-24 |
| Premiership Rugby | 2017/11/25 17:30 | Sale Sharks v Northampton | L | 18-15 |
| Premiership Rugby | 2017/11/18 13:00 | Worcester Warriors v Northampton | L | 30-15 |
| LV Cup | 2017/11/11 17:15 | Northampton v Newport Gwent Dragons | W | 41-7 |
| LV Cup | 2017/11/04 15:00 | Exeter Chiefs v Northampton | L | 43-28 |