[9] Harlequins 50-21 Northampton [10] 2017-12-30 16:00
Stadium: London Round: 12
Referee: JP Doyle Home Manager: Mark Mapletoft Away Manager: Alan Dickens
Head to Head
| Premiership Rugby | 2017/09/30 14:00 | Northampton v Harlequins | L | 30-22 |
| Premiership Rugby | 2017/05/06 15:00 | Northampton v Harlequins | L | 22-20 |
| Premiership Rugby | 2016/10/08 14:00 | Harlequins v Northampton | W | 20-9 |
| Premiership Rugby | 2016/03/27 14:15 | Northampton v Harlequins | L | 29-23 |
| Premiership Rugby | 2016/02/06 14:00 | Harlequins v Northampton | L | 23-27 |
| Premiership Rugby | 2015/02/27 19:45 | Northampton v Harlequins | L | 17-13 |
| Premiership Rugby | 2014/12/27 16:30 | Harlequins v Northampton | L | 25-30 |
| European Rugby Challenge Cup | 2014/04/25 19:00 | Northampton v Harlequins | L | 18-10 |