[9] Ayacucho FC 1-3 Cusco FC [17] 2021-09-11 18:15
Stadium: Estadio Ciudad de Cumaná Round: 10
Referee: Mike Palomino Home Manager: Walter Fiori Away Manager: Claudio Vivas
Head to Head
| Peru Liga 1 | 2020/11/20 16:00 | Ayacucho FC v Cusco FC | W | 3-1 |
| Peru Liga 1 | 2020/10/01 20:00 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2019/11/02 20:00 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2019/05/18 20:30 | Cusco FC v Ayacucho FC | L | 3-0 |
| Peru Liga 1 | 2018/11/25 20:30 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2018/08/26 20:30 | Cusco FC v Ayacucho FC | L | 2-1 |
| Peru Liga 1 | 2017/09/13 16:00 | Cusco FC v Ayacucho FC | L | 2-0 |
| Peru Liga 1 | 2017/06/10 17:30 | Ayacucho FC v Cusco FC | W | 2-1 |
Home History
| Peru Liga 1 | 2021/08/27 16:00 | Deportivo Binacional v Ayacucho FC | L | 3-1 |
| Peru Liga 1 | 2021/08/22 18:15 | Ayacucho FC v Cesar Vallejo | W | 2-1 |
| Peru Liga 1 | 2021/08/18 18:00 | Sport Huancayo v Ayacucho FC | D | 1-1 |
| Peru Liga 1 | 2021/08/14 18:15 | Ayacucho FC v Universitario de Deportes | D | 1-1 |
| Peru Liga 1 | 2021/08/06 16:00 | Deportivo Municipal v Ayacucho FC | W | 0-1 |
| Peru Liga 1 | 2021/08/02 22:00 | Ayacucho FC v CD Universidad San Martin | W | 1-0 |
| Peru Liga 1 | 2021/07/30 16:00 | Academia Deportiva Cantolao v Ayacucho FC | D | 2-2 |
| Peru Liga 1 | 2021/07/24 18:15 | Ayacucho FC v Sport Boys | L | 1-2 |
Away History
| Peru Liga 1 | 2021/08/27 20:30 | Cusco FC v Cienciano | W | 3-0 |
| Peru Liga 1 | 2021/08/22 23:00 | Sporting Cristal v Cusco FC | L | 4-1 |
| Peru Liga 1 | 2021/08/17 16:00 | Cusco FC v Carlos Manucci | L | 2-3 |
| Peru Liga 1 | 2021/08/13 16:00 | UTC Cajamarca v Cusco FC | L | 2-1 |
| Peru Liga 1 | 2021/08/08 16:00 | Cusco FC v Alianza Atletico | W | 3-0 |
| Peru Liga 1 | 2021/08/04 19:30 | FBC Melgar v Cusco FC | D | 2-2 |
| Peru Liga 1 | 2021/08/01 16:00 | Cusco FC v Alianza Universidad | L | 2-3 |
| Peru Liga 1 | 2021/07/25 16:00 | Cusco FC v Deportivo Binacional | D | 2-2 |