[9] Ayacucho FC 1-3 Cusco FC [17] 2021-09-11 18:15
Stadium: Estadio Ciudad de Cumaná Round: 10
Referee: Mike Palomino Home Manager: Walter Fiori Away Manager: Claudio Vivas
Head to Head
| Peru Liga 1 | 2020/11/20 16:00 | Ayacucho FC v Cusco FC | W | 3-1 |
| Peru Liga 1 | 2020/10/01 20:00 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2019/11/02 20:00 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2019/05/18 20:30 | Cusco FC v Ayacucho FC | L | 3-0 |
| Peru Liga 1 | 2018/11/25 20:30 | Ayacucho FC v Cusco FC | D | 1-1 |
| Peru Liga 1 | 2018/08/26 20:30 | Cusco FC v Ayacucho FC | L | 2-1 |
| Peru Liga 1 | 2017/09/13 16:00 | Cusco FC v Ayacucho FC | L | 2-0 |
| Peru Liga 1 | 2017/06/10 17:30 | Ayacucho FC v Cusco FC | W | 2-1 |
| Peru Liga 1 | 2016/07/03 18:15 | Ayacucho FC v Cusco FC | L | 1-2 |
| Peru Liga 1 | 2016/02/27 17:30 | Cusco FC v Ayacucho FC | L | 2-0 |
| Peru Liga 1 | 2015/09/03 16:00 | Ayacucho FC v Cusco FC | D | 2-2 |
| Peru Liga 1 | 2015/05/05 18:15 | Cusco FC v Ayacucho FC | L | 3-2 |
| Peru Liga 1 | 2014/11/09 18:15 | Ayacucho FC v Cusco FC | W | 2-1 |
| Peru Liga 1 | 2014/08/10 16:15 | Cusco FC v Ayacucho FC | L | 3-0 |