[6] FLA Panthers 4-1 TB Lightning [9] 2021-10-19 23:00
Stadium: Amalie Arena
Home Manager: Jon Cooper Away Manager: Joel Quenneville
Head to Head
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | W | 3-2 |
| NHL | 2021/05/27 00:00 | FLA Panthers v TB Lightning | L | 0-4 |
| NHL | 2021/05/25 00:00 | TB Lightning v FLA Panthers | W | 1-4 |
| NHL | 2021/05/22 16:30 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL | 2021/05/20 22:30 | FLA Panthers v TB Lightning | W | 6-5 |
| NHL | 2021/05/19 00:00 | TB Lightning v FLA Panthers | L | 3-1 |
Home History
| NHL | 2021/10/16 22:00 | NY Islanders v FLA Panthers | W | 1-5 |
| NHL | 2021/10/14 23:00 | PIT Penguins v FLA Panthers | W | 4-5 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | W | 3-2 |
| NHL Pre-Season | 2021/10/01 23:00 | DAL Stars v FLA Panthers | W | 3-6 |
| NHL Pre-Season | 2021/09/30 00:00 | FLA Panthers v DAL Stars | W | 4-3 |
| NHL Pre-Season | 2021/09/26 22:00 | FLA Panthers v NAS Predators | W | 3-1 |
Away History
| NHL | 2021/10/16 23:00 | TB Lightning v WAS Capitals | W | 2-1 |
| NHL | 2021/10/14 23:30 | TB Lightning v DET Red Wings | W | 7-6 |
| NHL | 2021/10/12 23:30 | PIT Penguins v TB Lightning | L | 6-2 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | W | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | W | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | L | 3-2 |
| NHL Pre-Season | 2021/10/03 00:00 | TB Lightning v NAS Predators | L | 1-6 |
| NHL Pre-Season | 2021/10/01 23:00 | CAR Hurricanes v TB Lightning | W | 5-8 |