[6] FLA Panthers 4-1 TB Lightning [9] 2021-10-19 23:00
Stadium: Amalie Arena
Home Manager: Jon Cooper Away Manager: Joel Quenneville
Head to Head
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | W | 3-2 |
| NHL | 2021/05/27 00:00 | FLA Panthers v TB Lightning | L | 0-4 |
| NHL | 2021/05/25 00:00 | TB Lightning v FLA Panthers | W | 1-4 |
| NHL | 2021/05/22 16:30 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL | 2021/05/20 22:30 | FLA Panthers v TB Lightning | W | 6-5 |
| NHL | 2021/05/19 00:00 | TB Lightning v FLA Panthers | L | 3-1 |
| NHL | 2021/05/16 23:30 | TB Lightning v FLA Panthers | L | 5-4 |
| NHL | 2021/05/10 23:00 | TB Lightning v FLA Panthers | W | 0-4 |
| NHL | 2021/05/08 23:00 | TB Lightning v FLA Panthers | W | 1-5 |
| NHL | 2021/04/17 23:00 | FLA Panthers v TB Lightning | W | 5-3 |
| NHL | 2021/04/15 23:00 | FLA Panthers v TB Lightning | L | 2-3 |
| NHL | 2021/03/21 20:00 | FLA Panthers v TB Lightning | L | 3-5 |
| NHL | 2021/02/16 00:00 | FLA Panthers v TB Lightning | W | 6-4 |
| NHL | 2021/02/14 00:00 | TB Lightning v FLA Panthers | L | 6-1 |
| NHL | 2021/02/12 00:00 | TB Lightning v FLA Panthers | W | 2-5 |
| NHL Pre-Season | 2020/07/29 16:00 | TB Lightning v FLA Panthers | L | 5-0 |
| NHL | 2019/12/24 00:00 | FLA Panthers v TB Lightning | L | 1-6 |
| NHL | 2019/12/11 00:00 | TB Lightning v FLA Panthers | L | 2-1 |
| NHL | 2019/10/05 23:00 | TB Lightning v FLA Panthers | W | 3-4 |
| NHL | 2019/10/03 23:00 | FLA Panthers v TB Lightning | L | 2-5 |
| NHL Pre-Season | 2019/09/28 23:00 | FLA Panthers v TB Lightning | W | 1-0 |
| NHL Pre-Season | 2019/09/26 23:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2019/09/24 23:00 | TB Lightning v FLA Panthers | W | 3-6 |
| NHL | 2019/02/10 23:00 | TB Lightning v FLA Panthers | L | 5-2 |
| NHL | 2018/12/02 00:00 | TB Lightning v FLA Panthers | L | 5-4 |
| NHL | 2018/11/22 00:30 | FLA Panthers v TB Lightning | L | 3-7 |
| NHL | 2018/10/06 23:00 | FLA Panthers v TB Lightning | L | 1-2 |
| NHL Pre-Season | 2018/09/29 23:00 | TB Lightning v FLA Panthers | L | 3-2 |