[63] Maria C O Serrano 7-5,6-1 Saisai Zheng [86] 2021-10-22 16:00
Stadium: Center Court Round: 27 Ground: Hardcourt outdoor
Home History
| WTA Tenerife | 2021/10/21 16:00 | Maria Camila Osorio v Mayar Sherif | 6-4,6-2 |
| WTA Tenerife | 2021/10/19 18:00 | Elina Svitolina v Maria Camila Osorio | 7-5,3-6,2-6 |
| WTA Indian Wells | 2021/10/07 01:15 | Maria Camila Osorio v Aliaksandra Sasnovich | 0-6,4-6 |
| WTA Chicago | 2021/09/28 15:30 | Maria Camila Osorio v Tereza Martincova | 3-6,5-7 |
| US Open Women | 2021/09/01 15:30 | Maria Camila Osorio v Ons Jabeur | 0-6,1-6 |
| US Open Women | 2021/08/30 20:05 | Ivana Jorovic v Maria Camila Osorio | 2-6,2-6 |
| WTA Chicago | 2021/08/23 19:10 | Maria Camila Osorio v Viktorija Golubic | 6-7,3-6 |
| WTA Cincinnati | 2021/08/14 14:00 | Anna Blinkova v Maria Camila Osorio | 6-3,6-0 |
Away History
| WTA Tenerife | 2021/10/21 09:30 | Saisai Zheng v Clara Tauson | 7-6,2-6,6-4 |
| WTA Tenerife | 2021/10/19 13:15 | Saisai Zheng v Rebeka Masarova | 6-4,6-2 |
| WTA Indian Wells | 2021/10/07 23:50 | Saisai Zheng v Magdalena Frech | 1-6,4-6 |
| ITF W60 Berkeley | 2021/09/29 20:50 | Saisai Zheng v Maria Kozyreva | 6-4,5-7,1-6 |
| WTA Columbus | 2021/09/25 15:00 | Saisai Zheng v Nuria Parrizas-Diaz | 7-5,3-6,4-6 |
| WTA Columbus | 2021/09/24 15:00 | Lauren Davis v Saisai Zheng | 6-1,2-6,2-6 |
| WTA Columbus | 2021/09/23 15:00 | Alexa Glatch v Saisai Zheng | 6-4,4-6,3-6 |
| WTA Columbus | 2021/09/21 21:20 | Asia Muhammad v Saisai Zheng | 7-6,3-6,6-7 |