[10] Chivas Guadalajara 1-0 Santos Laguna [13] 2022-03-06 03:00
Stadium: Estadio Akron Round: 9
Referee: Victor Alfonso Caceres Hernandez Home Manager: Marcelo Michel Leano Away Manager: Eduardo Fentanes
Head to Head
| Mexico Liga MX | 2021/08/16 00:06 | Santos Laguna v Chivas Guadalajara | D | 0-0 |
| Mexico Liga MX | 2021/04/04 22:00 | Chivas Guadalajara v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2020/08/03 00:00 | Santos Laguna v Chivas Guadalajara | L | 2-0 |
| Mexico Cup | 2019/11/07 03:00 | Santos Laguna v Chivas Guadalajara | L | 2-0 |
| Mexico Cup | 2019/08/08 00:00 | Chivas Guadalajara v Santos Laguna | W | 2-1 |
| Mexico Liga MX | 2019/07/21 23:45 | Santos Laguna v Chivas Guadalajara | L | 3-0 |
| Mexico Liga MX | 2019/01/28 00:06 | Santos Laguna v Chivas Guadalajara | L | 1-0 |
| Mexico Liga MX | 2018/08/12 23:00 | Chivas Guadalajara v Santos Laguna | L | 1-2 |
Home History
| Mexico Liga MX | 2022/03/03 03:00 | Atletico San Luis v Chivas Guadalajara | D | 2-2 |
| Mexico Liga MX | 2022/02/27 01:00 | Chivas Guadalajara v Puebla | L | 2-3 |
| Mexico Liga MX | 2022/02/20 03:00 | Leon v Chivas Guadalajara | L | 2-1 |
| Mexico Liga MX | 2022/02/12 23:00 | Chivas Guadalajara v Tigres UANL | L | 1-3 |
| Mexico Liga MX | 2022/02/10 01:00 | Juarez FC v Chivas Guadalajara | W | 1-3 |
| Mexico Liga MX | 2022/01/22 23:00 | Chivas Guadalajara v Queretaro | D | 1-1 |
| Mexico Liga MX | 2022/01/16 23:00 | Pachuca v Chivas Guadalajara | L | 2-1 |
| Mexico Liga MX | 2022/01/10 00:00 | Chivas Guadalajara v Mazatlan FC | W | 3-0 |
Away History
| Mexico Liga MX | 2022/03/03 03:00 | Santos Laguna v Unam Pumas | W | 3-2 |
| Mexico Liga MX | 2022/02/28 01:00 | Cruz Azul v Santos Laguna | W | 1-2 |
| CONCACAF Champions Cup | 2022/02/24 01:15 | CF Montreal v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2022/02/19 03:00 | Juarez FC v Santos Laguna | D | 0-0 |
| CONCACAF Champions Cup | 2022/02/16 03:00 | Santos Laguna v CF Montreal | W | 1-0 |
| Mexico Liga MX | 2022/02/13 03:00 | Santos Laguna v Club America | L | 2-3 |
| Mexico Liga MX | 2022/02/07 00:00 | Atlas v Santos Laguna | L | 2-1 |
| Club Friendly List | 2022/01/29 02:00 | Mazatlan FC v Santos Laguna | L | 2-1 |