[12] Atletico San Luis 2-0 Leon [6] 2022-04-09 22:00
Stadium: Alfonso Lastras Ramirez Round: 13
Referee: Luis Enrique Santander Aguirre Home Manager: Andre Jardine Away Manager: Ariel Holan
Head to Head
| Mexico Liga MX | 2021/10/02 22:00 | Leon v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2021/02/02 03:00 | Leon v Atletico San Luis | L | 3-1 |
| Mexico Liga MX | 2020/09/27 22:00 | Atletico San Luis v Leon | L | 0-2 |
| Mexico Liga MX | 2020/02/15 01:00 | Atletico San Luis v Leon | W | 3-1 |
| Mexico Liga MX | 2019/10/27 00:00 | Leon v Atletico San Luis | L | 3-2 |
| Mexico Cup | 2015/08/06 00:00 | Leon v Atletico San Luis | D | 3-3 |
| Mexico Cup | 2015/07/29 00:00 | Atletico San Luis v Leon | L | 1-2 |
Home History
| Mexico Liga MX | 2022/04/07 02:06 | Tijuana v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2022/04/02 02:00 | Atletico San Luis v Mazatlan FC | W | 1-0 |
| Mexico Liga MX | 2022/03/18 03:05 | Queretaro v Atletico San Luis | L | 2-1 |
| Mexico Liga MX | 2022/03/13 23:00 | Atletico San Luis v Puebla | W | 2-1 |
| Mexico Liga MX | 2022/03/03 03:00 | Atletico San Luis v Chivas Guadalajara | D | 2-2 |
| Mexico Liga MX | 2022/02/26 23:06 | Monterrey v Atletico San Luis | W | 0-2 |
| Mexico Liga MX | 2022/02/20 01:00 | Tigres UANL v Atletico San Luis | L | 2-1 |
| Mexico Liga MX | 2022/02/12 23:00 | Atletico San Luis v Toluca | L | 0-1 |
Away History
| Mexico Liga MX | 2022/04/03 22:00 | Leon v Queretaro | D | 1-1 |
| Mexico Liga MX | 2022/03/21 03:00 | Mazatlan FC v Leon | W | 1-2 |
| CONCACAF Champions Cup | 2022/03/18 00:30 | Leon v Seattle Sounders | D | 1-1 |
| Mexico Liga MX | 2022/03/12 23:00 | Leon v Tigres UANL | L | 0-3 |
| CONCACAF Champions Cup | 2022/03/09 03:00 | Seattle Sounders v Leon | L | 3-0 |
| Mexico Liga MX | 2022/03/05 03:00 | Juarez FC v Leon | W | 0-1 |
| Mexico Liga MX | 2022/03/02 03:00 | Leon v Monterrey | D | 0-0 |
| Mexico Liga MX | 2022/02/26 01:00 | Necaxa v Leon | W | 0-1 |