[13] Atletico San Luis 2-0 Unam Pumas [9] 2022-04-21 00:00
Stadium: Alfonso Lastras Ramirez Round: 15
Referee: Marco Antonio Ortiz Nava Home Manager: Andre Jardine Away Manager: Andres Lillini
Head to Head
| Mexico Liga MX | 2021/08/08 17:00 | Unam Pumas v Atletico San Luis | W | 1-3 |
| Mexico Liga MX | 2021/03/20 23:00 | Atletico San Luis v Unam Pumas | L | 0-1 |
| Mexico Liga MX | 2020/09/13 17:00 | Unam Pumas v Atletico San Luis | L | 3-0 |
| Mexico Liga MX | 2020/02/09 18:00 | Unam Pumas v Atletico San Luis | L | 4-0 |
| Mexico Cup | 2019/10/03 02:00 | Atletico San Luis v Unam Pumas | L | 0-4 |
| Mexico Cup | 2019/08/01 02:00 | Unam Pumas v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2019/07/20 22:00 | Atletico San Luis v Unam Pumas | L | 0-2 |
| World Club Friendlies | 2018/07/08 00:03 | Atletico San Luis v Unam Pumas | W | 2-0 |
Home History
| Mexico Liga MX | 2022/04/16 00:00 | Necaxa v Atletico San Luis | L | 4-2 |
| Mexico Liga MX | 2022/04/09 22:00 | Atletico San Luis v Leon | W | 2-0 |
| Mexico Liga MX | 2022/04/07 02:06 | Tijuana v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2022/04/02 02:00 | Atletico San Luis v Mazatlan FC | W | 1-0 |
| Mexico Liga MX | 2022/03/18 03:05 | Queretaro v Atletico San Luis | L | 2-1 |
| Mexico Liga MX | 2022/03/13 23:00 | Atletico San Luis v Puebla | W | 2-1 |
| Mexico Liga MX | 2022/03/03 03:00 | Atletico San Luis v Chivas Guadalajara | D | 2-2 |
| Mexico Liga MX | 2022/02/26 23:06 | Monterrey v Atletico San Luis | W | 0-2 |
Away History
| Mexico Liga MX | 2022/04/17 17:00 | Unam Pumas v Monterrey | W | 2-0 |
| CONCACAF Champions Cup | 2022/04/13 02:00 | Cruz Azul v Unam Pumas | D | 0-0 |
| Mexico Liga MX | 2022/04/09 00:00 | Puebla v Unam Pumas | D | 2-2 |
| CONCACAF Champions Cup | 2022/04/06 02:00 | Unam Pumas v Cruz Azul | W | 2-1 |
| Mexico Liga MX | 2022/04/03 03:00 | Juarez FC v Unam Pumas | W | 0-1 |
| Mexico Liga MX | 2022/03/26 23:00 | Unam Pumas v Mazatlan FC | D | 1-1 |
| Mexico Liga MX | 2022/03/19 23:00 | Unam Pumas v Necaxa | L | 1-3 |
| CONCACAF Champions Cup | 2022/03/17 02:15 | Unam Pumas v New England Revolution | W | 3-0 |