[5] Deportivo Maldonado 1-2 Danubio [6] 2022-02-15 00:30
Stadium: Estadio Domingo Burgueno Miguel Round: 2
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Francisco Palladino Away Manager: Jorge Fossati
Head to Head
| Uruguay Clausura | 2021/03/23 19:00 | Danubio v Deportivo Maldonado | D | 2-2 |
| Uruguay Torneo Intermedio | 2020/12/13 23:00 | Deportivo Maldonado v Danubio | D | 1-1 |
| Uruguay Apertura | 2020/10/06 00:15 | Deportivo Maldonado v Danubio | D | 0-0 |
Home History
| Uruguay Apertura | 2022/02/06 23:00 | Nacional De Football v Deportivo Maldonado | W | 2-3 |
| Uruguay Clausura | 2021/12/04 20:00 | Boston River v Deportivo Maldonado | L | 2-1 |
| Uruguay Clausura | 2021/11/25 12:45 | Deportivo Maldonado v Cerrito | L | 0-1 |
| Uruguay Clausura | 2021/11/19 19:30 | Atletico Fenix Montevideo v Deportivo Maldonado | L | 2-1 |
| Uruguay Clausura | 2021/11/13 19:30 | Deportivo Maldonado v Nacional De Football | W | 1-0 |
| Uruguay Clausura | 2021/11/09 00:00 | Plaza Colonia v Deportivo Maldonado | L | 1-0 |
| Uruguay Clausura | 2021/11/02 12:45 | Deportivo Maldonado v Villa Espanola | L | 0-1 |
| Uruguay Clausura | 2021/10/30 19:00 | IA Sud America v Deportivo Maldonado | D | 1-1 |
Away History
| Uruguay Clausura | 2022/02/08 23:00 | Cerrito v Danubio | W | 0-1 |
| America Friendlies | 2022/01/24 23:30 | Danubio v Barracas Central | L | 0-1 |
| America Friendlies | 2022/01/18 20:30 | Danubio v Belgrano | L | 0-1 |
| America Friendlies | 2022/01/17 00:30 | Defensor Sporting v Danubio | W | 0-2 |
| Uruguay Segunda | 2021/11/24 01:15 | Defensor Sporting v Danubio | W | 0-1 |
| Uruguay Segunda | 2021/11/18 01:15 | Danubio v Cerro | D | 0-0 |
| Uruguay Segunda | 2021/11/10 01:15 | Rocha v Danubio | W | 1-2 |
| Uruguay Segunda | 2021/11/01 22:45 | Albion FC v Danubio | L | 2-1 |