[5] Deportivo Maldonado 1-2 Danubio [6] 2022-02-15 00:30
Stadium: Estadio Domingo Burgueno Miguel Round: 2
Referee: Leodan Frankin Gonzalez Cabrera Home Manager: Francisco Palladino Away Manager: Jorge Fossati
Head to Head
| Uruguay Clausura | 2021/03/23 19:00 | Danubio v Deportivo Maldonado | D | 2-2 |
| Uruguay Torneo Intermedio | 2020/12/13 23:00 | Deportivo Maldonado v Danubio | D | 1-1 |
| Uruguay Apertura | 2020/10/06 00:15 | Deportivo Maldonado v Danubio | D | 0-0 |