[13] Mushuc Runa 2-0 Guayaquil City [7] 2022-04-30 20:00
Stadium: Estadio Bellavista Round: 11
Referee: Alex Fabricio Cajas Torres Home Manager: Geovanny Cumbicus Away Manager: Pool Gavilanez
Head to Head
| Ecuador LigaPro Serie A | 2021/11/21 20:30 | Mushuc Runa v Guayaquil City | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/05/29 21:30 | Guayaquil City v Mushuc Runa | D | 0-0 |
| Ecuador LigaPro Serie A | 2020/11/14 18:00 | Guayaquil City v Mushuc Runa | L | 3-2 |
| Ecuador LigaPro Serie A | 2020/09/26 19:45 | Mushuc Runa v Guayaquil City | W | 2-1 |
| Ecuador LigaPro Serie A | 2019/08/25 19:45 | Guayaquil City v Mushuc Runa | L | 4-2 |
| Ecuador LigaPro Serie A | 2019/04/06 20:00 | Mushuc Runa v Guayaquil City | W | 3-2 |
| Ecuador LigaPro Serie A | 2016/10/30 17:00 | Mushuc Runa v Guayaquil City | L | 0-2 |
| Ecuador LigaPro Serie A | 2016/09/10 21:00 | Guayaquil City v Mushuc Runa | D | 0-0 |
Home History
| Ecuador LigaPro Serie A | 2022/04/24 19:30 | LDU Quito v Mushuc Runa | L | 3-2 |
| Ecuador LigaPro Serie A | 2022/04/21 18:00 | Mushuc Runa v Macara | D | 0-0 |
| Ecuador LigaPro Serie A | 2022/04/16 00:00 | Gualaceo SC v Mushuc Runa | L | 3-2 |
| Ecuador LigaPro Serie A | 2022/04/09 19:30 | Mushuc Runa v Delfin SC | L | 1-2 |
| Ecuador LigaPro Serie A | 2022/04/03 19:00 | Orense v Mushuc Runa | D | 0-0 |
| Ecuador LigaPro Serie A | 2022/03/20 01:00 | Mushuc Runa v Barcelona Guayaquil | D | 1-1 |
| Copa Sudamericana | 2022/03/17 00:30 | LDU Quito v Mushuc Runa | D | 1-1 |
| Ecuador LigaPro Serie A | 2022/03/12 20:00 | Mushuc Runa v Cumbaya FC | W | 4-2 |
Away History
| Ecuador LigaPro Serie A | 2022/04/26 00:00 | Guayaquil City v Cumbaya FC | W | 4-1 |
| Ecuador LigaPro Serie A | 2022/04/16 22:30 | Guayaquil City v SD Aucas | W | 4-0 |
| Ecuador LigaPro Serie A | 2022/04/10 18:00 | Independiente del Valle v Guayaquil City | D | 0-0 |
| Ecuador LigaPro Serie A | 2022/04/03 21:30 | Guayaquil City v Tecnico Universitario | L | 0-1 |
| Ecuador LigaPro Serie A | 2022/03/20 21:30 | Macara v Guayaquil City | L | 2-0 |
| Ecuador LigaPro Serie A | 2022/03/15 00:00 | Guayaquil City v Delfin SC | D | 1-1 |
| Ecuador LigaPro Serie A | 2022/03/05 00:00 | Emelec v Guayaquil City | D | 2-2 |
| Ecuador LigaPro Serie A | 2022/02/26 22:30 | Universidad Catolica del Ecuador v Guayaquil City | D | 1-1 |