[13] Mushuc Runa 2-0 Guayaquil City [7] 2022-04-30 20:00
Stadium: Estadio Bellavista Round: 11
Referee: Alex Fabricio Cajas Torres Home Manager: Geovanny Cumbicus Away Manager: Pool Gavilanez
Head to Head
| Ecuador LigaPro Serie A | 2021/11/21 20:30 | Mushuc Runa v Guayaquil City | W | 1-0 |
| Ecuador LigaPro Serie A | 2021/05/29 21:30 | Guayaquil City v Mushuc Runa | D | 0-0 |
| Ecuador LigaPro Serie A | 2020/11/14 18:00 | Guayaquil City v Mushuc Runa | L | 3-2 |
| Ecuador LigaPro Serie A | 2020/09/26 19:45 | Mushuc Runa v Guayaquil City | W | 2-1 |
| Ecuador LigaPro Serie A | 2019/08/25 19:45 | Guayaquil City v Mushuc Runa | L | 4-2 |
| Ecuador LigaPro Serie A | 2019/04/06 20:00 | Mushuc Runa v Guayaquil City | W | 3-2 |
| Ecuador LigaPro Serie A | 2016/10/30 17:00 | Mushuc Runa v Guayaquil City | L | 0-2 |
| Ecuador LigaPro Serie A | 2016/09/10 21:00 | Guayaquil City v Mushuc Runa | D | 0-0 |
| Ecuador LigaPro Serie A | 2016/07/24 19:00 | Mushuc Runa v Guayaquil City | L | 0-1 |
| Ecuador LigaPro Serie A | 2016/02/06 00:00 | Guayaquil City v Mushuc Runa | L | 3-1 |
| Ecuador LigaPro Serie A | 2015/10/18 17:00 | Mushuc Runa v Guayaquil City | D | 1-1 |
| Ecuador LigaPro Serie A | 2015/09/05 21:30 | Guayaquil City v Mushuc Runa | D | 2-2 |
| Ecuador LigaPro Serie A | 2015/05/17 17:00 | Mushuc Runa v Guayaquil City | W | 1-0 |
| Ecuador LigaPro Serie A | 2015/02/28 21:00 | Guayaquil City v Mushuc Runa | L | 2-0 |