[3] Cobreloa 1-0 Club Deportes Santa Cruz [14] 2022-06-02 19:00
Stadium: Municipal de Calama Round: 5
Head to Head
| Chile Primera B | 2021/11/06 23:30 | Club Deportes Santa Cruz v Cobreloa | D | 2-2 |
| Chile Primera B | 2021/08/08 15:00 | Cobreloa v Club Deportes Santa Cruz | L | 0-1 |
| Chile Primera B | 2020/12/10 13:00 | Club Deportes Santa Cruz v Cobreloa | L | 4-1 |
| Chile Primera B | 2020/09/06 15:00 | Cobreloa v Club Deportes Santa Cruz | L | 0-1 |
| Chile Primera B | 2019/06/02 19:00 | Club Deportes Santa Cruz v Cobreloa | L | 1-0 |
Home History
| Chile Primera B | 2022/05/28 16:30 | Santiago Morning v Cobreloa | W | 0-1 |
| Chile Primera B | 2022/05/22 21:30 | Cobreloa v CD Arturo Fernández Vial | W | 1-0 |
| Chile Primera B | 2022/05/17 22:00 | Deportes Temuco v Cobreloa | L | 2-0 |
| Chile Primera B | 2022/05/13 00:30 | Cobreloa v Santiago Wanderers | D | 1-1 |
| Chile Primera B | 2022/04/29 22:00 | Union San Felipe v Cobreloa | D | 1-1 |
| Chile Primera B | 2022/04/24 00:00 | Cobreloa v Deportes Recoleta | W | 3-0 |
| Chile Primera B | 2022/04/21 00:30 | Cobreloa v Barnechea | W | 3-2 |
| Chile Primera B | 2022/04/17 00:00 | Deportes Iquique v Cobreloa | L | 2-0 |
Away History
| Chile Primera B | 2022/05/27 22:00 | Club Deportes Santa Cruz v Santiago Wanderers | W | 2-0 |
| Chile Primera B | 2022/05/22 21:30 | Melipilla v Club Deportes Santa Cruz | L | 1-0 |
| Chile Primera B | 2022/05/18 00:30 | Club Deportes Santa Cruz v San Luis Quillota | W | 2-0 |
| Chile Primera B | 2022/05/12 22:00 | Union San Felipe v Club Deportes Santa Cruz | L | 2-1 |
| Chile Primera B | 2022/05/08 00:00 | Club Deportes Santa Cruz v Deportes Recoleta | W | 1-0 |
| Chile Primera B | 2022/04/30 18:30 | Puerto Montt v Club Deportes Santa Cruz | L | 3-0 |
| Chile Primera B | 2022/04/26 00:30 | Club Deportes Santa Cruz v Deportes Copiapo | D | 2-2 |
| Chile Primera B | 2022/04/21 00:30 | Rangers de Talca v Club Deportes Santa Cruz | L | 2-1 |