[49] Francisco Cerundolo 4-6,3-6 John Isner [27] 2022-05-10 11:25
Stadium: Court 1 Round: 24 Ground: Clay
Home History
| ATP Rome | 2022/05/08 11:15 | Francisco Cerundolo v Joao Sousa | 6-2,7-6 |
| ATP Rome | 2022/05/07 11:40 | Francisco Cerundolo v Yoshihito Nishioka | 7-6,6-3 |
| ATP Madrid | 2022/04/30 09:00 | Francisco Cerundolo v Alejandro Moro Canas | 0-6,4-6 |
| ATP Munich | 2022/04/23 09:00 | Francisco Cerundolo v Egor Gerasimov | 6-7,1-6 |
| ATP Miami | 2022/04/01 17:00 | Francisco Cerundolo v Casper Ruud | 4-6,1-6 |
| ATP Miami | 2022/03/29 18:55 | Francisco Cerundolo v Frances Tiafoe | 6-7,7-6,6-2 |
| ATP Miami | 2022/03/27 23:00 | Francisco Cerundolo v Gael Monfils | 6-2,6-3 |
| ATP Miami | 2022/03/23 15:00 | Tallon Griekspoor v Francisco Cerundolo | 5-7,6-4,3-6 |
Away History
| ATP Madrid | 2022/05/04 12:25 | Cameron Norrie v John Isner | 6-4,6-7,6-4 |
| ATP Madrid | 2022/05/01 13:00 | Filip Krajinovic v John Isner | 6-7,4-6 |
| ATP Houston | 2022/04/10 19:00 | Reilly Opelka v John Isner | 6-3,7-6 |
| ATP Houston | 2022/04/09 19:30 | John Isner v Cristian Garin | 4-6,6-3,6-4 |
| ATP Houston | 2022/04/08 23:00 | Frances Tiafoe v John Isner | 4-6,6-2,3-6 |
| ATP Houston | 2022/04/08 01:55 | Steve Johnson v John Isner | 7-6,6-7,3-6 |
| ATP Miami | 2022/03/25 18:05 | John Isner v Hugo Gaston | 6-7,4-6 |
| ATP Indian Wells | 2022/03/16 21:30 | John Isner v Grigor Dimitrov | 3-6,6-7 |