[2] Oriente Petrolero 1-2 Real Santa Cruz [8] 2022-05-14 20:00
Stadium: Estadio Ramon Tahuichi Aguilera Round: 15
Head to Head
| Bolivia Apertura | 2022/04/02 19:00 | Real Santa Cruz v Oriente Petrolero | L | 2-1 |
| Bolivia Apertura | 2021/12/05 00:30 | Oriente Petrolero v Real Santa Cruz | W | 2-0 |
| Bolivia Apertura | 2021/08/07 19:00 | Real Santa Cruz v Oriente Petrolero | D | 0-0 |
| Bolivia Apertura | 2020/12/16 23:30 | Oriente Petrolero v Real Santa Cruz | W | 3-2 |
| Bolivia Apertura | 2020/02/16 19:00 | Real Santa Cruz v Oriente Petrolero | W | 1-5 |
Home History
| Bolivia Apertura | 2022/05/12 00:00 | Universitario de Sucre v Oriente Petrolero | D | 1-1 |
| Bolivia Apertura | 2022/05/08 23:30 | Blooming v Oriente Petrolero | W | 1-2 |
| Copa Sudamericana | 2022/05/05 22:15 | Union Santa Fe v Oriente Petrolero | L | 2-0 |
| Bolivia Apertura | 2022/05/02 00:00 | Oriente Petrolero v Atletico Palmaflor Vinto | W | 2-1 |
| Copa Sudamericana | 2022/04/29 00:30 | Oriente Petrolero v Junior | L | 1-3 |
| Bolivia Apertura | 2022/04/24 21:15 | Guabira v Oriente Petrolero | D | 0-0 |
| Bolivia Apertura | 2022/04/20 22:30 | Club Aurora v Oriente Petrolero | D | 1-1 |
| Bolivia Apertura | 2022/04/17 23:30 | Oriente Petrolero v The Strongest | D | 1-1 |
Away History
| Bolivia Apertura | 2022/05/12 19:00 | Club Aurora v Real Santa Cruz | W | 2-4 |
| Bolivia Apertura | 2022/05/08 19:00 | Always Ready v Real Santa Cruz | L | 5-0 |
| Bolivia Apertura | 2022/04/30 19:00 | The Strongest v Real Santa Cruz | D | 1-1 |
| Bolivia Apertura | 2022/04/24 19:00 | Real Santa Cruz v Nacional Potosi | W | 3-2 |
| Bolivia Apertura | 2022/04/21 22:15 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2022/04/16 00:00 | Universitario de Sucre v Real Santa Cruz | W | 2-3 |
| Bolivia Apertura | 2022/04/09 19:00 | Atletico Palmaflor Vinto v Real Santa Cruz | L | 2-1 |
| Bolivia Apertura | 2022/04/02 19:00 | Real Santa Cruz v Oriente Petrolero | W | 2-1 |