[7] Minnesota 34-7 Michigan State [8] 2022-09-24 19:30
Stadium: Spartan Stadium Round: 1
Home Manager: Melvin Tucker Away Manager: P.J. Fleck
Head to Head
| NCAAF | 2017/10/15 00:00 | Michigan State v Minnesota | L | 30-27 |
| NCAAF | 2012/11/24 12:00 | Minnesota v Michigan State | L | 10-26 |
| NCAAF | 2011/11/05 12:00 | Michigan State v Minnesota | L | 31-24 |
| NCAAF | 2010/11/06 12:00 | Michigan State v Minnesota | L | 31-8 |
| NCAAF | 2009/10/31 12:00 | Minnesota v Michigan State | W | 42-34 |
| NCAAF | 2006/11/11 12:00 | Michigan State v Minnesota | W | 18-31 |
| NCAAF | 2005/11/12 12:00 | Minnesota v Michigan State | W | 41-18 |
| NCAAF | 2004/10/16 12:00 | Michigan State v Minnesota | L | 51-17 |
Home History
| NCAAF | 2022/09/17 19:30 | Colorado v Minnesota | W | 7-49 |
| NCAAF | 2022/09/10 16:00 | Western Illinois v Minnesota | W | 10-62 |
| NCAAF | 2022/09/02 01:00 | New Mexico State v Minnesota | W | 0-38 |
| NCAAF Bowl Games | 2021/12/29 03:15 | West Virginia v Minnesota | W | 6-18 |
| NCAAF | 2021/11/27 21:00 | Wisconsin v Minnesota | W | 13-23 |
| NCAAF | 2021/11/20 20:30 | Minnesota v Indiana | W | 35-14 |
| NCAAF | 2021/11/13 20:30 | Minnesota v Iowa | L | 22-27 |
| NCAAF | 2021/11/06 16:00 | Illinois v Minnesota | L | 14-6 |
Away History
| NCAAF | 2022/09/17 23:30 | Michigan State v Washington | L | 28-39 |
| NCAAF | 2022/09/10 20:00 | Akron v Michigan State | W | 0-52 |
| NCAAF | 2022/09/02 23:00 | Western Michigan v Michigan State | W | 13-35 |
| NCAAF Bowl Games | 2021/12/31 00:00 | Pittsburgh v Michigan State | W | 21-31 |
| NCAAF | 2021/11/27 20:30 | Penn State v Michigan State | W | 27-30 |
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | L | 7-56 |
| NCAAF | 2021/11/13 21:00 | Maryland v Michigan State | W | 21-40 |
| NCAAF | 2021/11/06 19:30 | Michigan State v Purdue | L | 29-40 |