[6] Santos Laguna 4-1 Atletico San Luis [9] 2022-08-29 00:05
Stadium: Estadio TSM Corona Round: 11
Referee: Fernando Guerrero Ramirez Home Manager: Eduardo Fentanes Away Manager: Andre Jardine
Head to Head
| Mexico Liga MX | 2022/05/01 21:00 | Atletico San Luis v Santos Laguna | W | 1-3 |
| Mexico Liga MX | 2021/11/21 01:00 | Santos Laguna v Atletico San Luis | W | 2-0 |
| Mexico Liga MX | 2021/11/08 01:06 | Santos Laguna v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2021/02/19 03:00 | Atletico San Luis v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2020/10/26 01:06 | Santos Laguna v Atletico San Luis | W | 2-1 |
| Mexico Liga MX | 2019/09/21 22:00 | Atletico San Luis v Santos Laguna | W | 2-3 |
| Mexico Cup | 2015/02/18 01:00 | Santos Laguna v Atletico San Luis | W | 3-0 |
| Mexico Cup | 2015/02/04 03:00 | Atletico San Luis v Santos Laguna | D | 0-0 |
Home History
| Mexico Liga MX | 2022/08/26 02:05 | Tijuana v Santos Laguna | W | 0-2 |
| Mexico Liga MX | 2022/08/21 17:00 | Unam Pumas v Santos Laguna | W | 1-5 |
| Mexico Liga MX | 2022/08/19 00:00 | Santos Laguna v Leon | W | 2-1 |
| Mexico Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | L | 2-0 |
| Mexico Liga MX | 2022/08/07 02:05 | Santos Laguna v Cruz Azul | W | 4-0 |
| Mexico Liga MX | 2022/08/01 00:05 | Santos Laguna v Atlas | W | 1-0 |
| Mexico Liga MX | 2022/07/23 22:00 | Toluca v Santos Laguna | L | 2-1 |
| Mexico Liga MX | 2022/07/17 00:05 | Santos Laguna v Chivas Guadalajara | D | 1-1 |
Away History
| Mexico Liga MX | 2022/08/21 22:00 | Atletico San Luis v Toluca | W | 1-0 |
| Mexico Liga MX | 2022/08/19 02:05 | Atletico San Luis v Unam Pumas | W | 3-2 |
| Mexico Liga MX | 2022/08/12 02:00 | Queretaro v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2022/08/07 21:00 | Atletico San Luis v Necaxa | L | 1-2 |
| Mexico Liga MX | 2022/08/04 01:00 | Juarez FC v Atletico San Luis | D | 1-1 |
| Mexico Liga MX | 2022/07/31 02:05 | Puebla v Atletico San Luis | D | 0-0 |
| Mexico Liga MX | 2022/07/27 02:05 | Atletico San Luis v Cruz Azul | D | 0-0 |
| Mexico Liga MX | 2022/07/23 00:00 | Mazatlan FC v Atletico San Luis | D | 1-1 |