[16] CHI Blackhawks 3-4 BUF Sabres [14] 2022-10-29 23:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Luke Richardson
Head to Head
| NHL | 2022/04/29 23:00 | CHI Blackhawks v BUF Sabres | L | 2-3 |
| NHL | 2022/03/29 00:30 | BUF Sabres v CHI Blackhawks | L | 6-5 |
| NHL | 2019/11/18 00:00 | BUF Sabres v CHI Blackhawks | W | 1-4 |
| NHL | 2019/03/08 01:30 | BUF Sabres v CHI Blackhawks | W | 4-5 |
| NHL | 2019/02/02 00:00 | CHI Blackhawks v BUF Sabres | W | 7-3 |
| NHL | 2018/03/17 17:00 | CHI Blackhawks v BUF Sabres | L | 3-5 |
| NHL | 2017/12/09 01:30 | BUF Sabres v CHI Blackhawks | W | 2-3 |
| NHL | 2017/02/19 23:00 | CHI Blackhawks v BUF Sabres | W | 5-1 |
Home History
| NHL | 2022/10/28 00:30 | EDM Oilers v CHI Blackhawks | L | 6-5 |
| NHL | 2022/10/26 00:30 | FLA Panthers v CHI Blackhawks | W | 2-4 |
| NHL | 2022/10/23 18:00 | SEA Kraken v CHI Blackhawks | W | 4-5 |
| NHL | 2022/10/22 00:30 | DET Red Wings v CHI Blackhawks | W | 3-4 |
| NHL | 2022/10/16 02:00 | CHI Blackhawks v SJ Sharks | W | 5-2 |
| NHL | 2022/10/14 02:00 | CHI Blackhawks v VGS Golden Knights | L | 0-1 |
| NHL | 2022/10/13 01:30 | CHI Blackhawks v COL Avalanche | L | 2-5 |
| NHL Pre-Season | 2022/10/08 19:00 | CHI Blackhawks v STL Blues | L | 0-6 |
Away History
| NHL | 2022/10/27 23:00 | MON Canadiens v BUF Sabres | L | 3-2 |
| NHL | 2022/10/26 02:00 | BUF Sabres v SEA Kraken | L | 1-5 |
| NHL | 2022/10/23 02:00 | BUF Sabres v VAN Canucks | W | 5-1 |
| NHL | 2022/10/21 01:30 | BUF Sabres v CAL Flames | W | 6-3 |
| NHL | 2022/10/19 01:00 | BUF Sabres v EDM Oilers | W | 4-2 |
| NHL | 2022/10/15 17:00 | FLA Panthers v BUF Sabres | L | 4-3 |
| NHL | 2022/10/13 23:00 | OTT Senators v BUF Sabres | W | 1-4 |
| NHL Pre-Season | 2022/10/07 23:00 | BUF Sabres v PIT Penguins | L | 1-7 |