[16] CHI Blackhawks 3-4 BUF Sabres [14] 2022-10-29 23:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Luke Richardson
Head to Head
| NHL | 2022/04/29 23:00 | CHI Blackhawks v BUF Sabres | L | 2-3 |
| NHL | 2022/03/29 00:30 | BUF Sabres v CHI Blackhawks | L | 6-5 |
| NHL | 2019/11/18 00:00 | BUF Sabres v CHI Blackhawks | W | 1-4 |
| NHL | 2019/03/08 01:30 | BUF Sabres v CHI Blackhawks | W | 4-5 |
| NHL | 2019/02/02 00:00 | CHI Blackhawks v BUF Sabres | W | 7-3 |
| NHL | 2018/03/17 17:00 | CHI Blackhawks v BUF Sabres | L | 3-5 |
| NHL | 2017/12/09 01:30 | BUF Sabres v CHI Blackhawks | W | 2-3 |
| NHL | 2017/02/19 23:00 | CHI Blackhawks v BUF Sabres | W | 5-1 |
| NHL | 2017/01/06 01:30 | BUF Sabres v CHI Blackhawks | W | 3-4 |