Stadium: Hancock Stadium Round: 1
Home Manager: Brock Spack Away Manager: Landon Fox
| NCAAF | 2022/09/03 23:00 | Valparaiso v Indiana Wesleyan Wildcats | W | 20-17 |
| NCAAF | 2021/11/20 19:00 | Morehead State v Valparaiso | L | 51-38 |
| NCAAF | 2021/11/13 17:00 | Valparaiso v Butler | W | 47-3 |
| NCAAF | 2021/11/06 18:00 | Presbyterian v Valparaiso | W | 55-65 |
| NCAAF | 2021/10/30 20:00 | Valparaiso v San Diego | L | 14-21 |
| NCAAF | 2021/10/23 17:00 | Dayton v Valparaiso | W | 28-45 |
| NCAAF | 2021/10/09 18:00 | Valparaiso v St. Thomas (MN) | L | 13-20 |
| NCAAF | 2021/10/02 17:00 | Marist v Valparaiso | L | 27-24 |
| NCAAF | 2022/09/03 23:00 | Illinois State v Wisconsin | L | 0-38 |
| NCAAF | 2021/11/20 18:00 | Indiana State v Illinois State | L | 15-10 |
| NCAAF | 2021/11/13 20:00 | Illinois State v North Dakota | L | 7-14 |
| NCAAF | 2021/11/06 17:00 | Northern Iowa v Illinois State | W | 10-17 |
| NCAAF | 2021/10/30 20:00 | Illinois State v Western Illinois | L | 31-38 |
| NCAAF | 2021/10/23 18:00 | Illinois State v South Dakota | W | 20-14 |
| NCAAF | 2021/10/16 19:00 | North Dakota State v Illinois State | L | 20-0 |
| NCAAF | 2021/10/02 18:00 | Missouri St v Illinois State | L | 41-20 |