Stadium: Memorial Stadium (Terre Haute) Round: 1
Home Manager: Curt Mallory Away Manager: Bobby Petrino
| NCAAF | 2021/10/16 19:00 | Indiana State v Missouri St | W | 7-37 |
| NCAAF | 2019/11/23 20:00 | Indiana State v Missouri St | L | 51-24 |
| NCAAF | 2018/10/13 18:00 | Missouri St v Indiana State | W | 29-26 |
| NCAAF | 2017/10/28 19:00 | Missouri St v Indiana State | W | 59-20 |
| NCAAF | 2022/11/12 20:00 | Youngstown State v Missouri St | W | 22-25 |
| NCAAF | 2022/11/05 18:00 | Missouri St v South Dakota | L | 13-20 |
| NCAAF | 2022/10/29 19:00 | Western Illinois v Missouri St | W | 14-64 |
| NCAAF | 2022/10/22 21:00 | Missouri St v Northern Iowa | L | 20-41 |
| NCAAF | 2022/10/08 19:00 | SO Illinois v Missouri St | L | 38-21 |
| NCAAF | 2022/10/01 17:00 | Missouri St v North Dakota | L | 31-48 |
| NCAAF | 2022/09/24 19:00 | South Dakota State v Missouri St | L | 28-14 |
| NCAAF | 2022/09/17 23:00 | Missouri St v Arkansas | L | 27-38 |
| NCAAF | 2022/11/12 19:00 | Indiana State v Western Illinois | W | 21-0 |
| NCAAF | 2022/11/05 17:00 | North Dakota v Indiana State | L | 42-7 |
| NCAAF | 2022/10/29 19:00 | Indiana State v South Dakota State | L | 7-49 |
| NCAAF | 2022/10/22 17:00 | Illinois State v Indiana State | L | 27-21 |
| NCAAF | 2022/10/15 18:00 | Indiana State v Youngstown State | L | 42-48 |
| NCAAF | 2022/10/08 17:00 | North Dakota State v Indiana State | L | 31-26 |
| NCAAF | 2022/10/01 21:00 | Indiana State v Northern Iowa | L | 14-20 |
| NCAAF | 2022/09/17 17:00 | Montana v Indiana State | L | 49-14 |