Stadium: Dana J. Dykhouse Stadium Round: 1
Home Manager: John Stiegelmeier Away Manager: Brock Spack
| NCAAF | 2019/11/09 20:00 | Illinois State v South Dakota State | W | 27-18 |
| NCAAF | 2018/10/27 17:00 | Illinois State v South Dakota State | L | 28-38 |
| NCAAF | 2017/11/11 20:00 | South Dakota State v Illinois State | L | 27-24 |
| NCAAF | 2022/11/05 19:00 | Youngstown State v Illinois State | L | 19-17 |
| NCAAF | 2022/10/29 19:30 | Illinois State v North Dakota State | L | 7-24 |
| NCAAF | 2022/10/22 17:00 | Illinois State v Indiana State | W | 27-21 |
| NCAAF | 2022/10/15 19:00 | South Dakota v Illinois State | W | 10-12 |
| NCAAF | 2022/10/08 21:00 | Illinois State v Northern Iowa | W | 23-21 |
| NCAAF | 2022/10/01 23:30 | SO Illinois v Illinois State | L | 19-14 |
| NCAAF | 2022/09/17 23:30 | Eastern Illinois v Illinois State | W | 7-35 |
| NCAAF | 2022/09/10 23:30 | Valparaiso v Illinois State | W | 21-28 |
| NCAAF | 2022/11/05 21:00 | South Dakota State v Northern Iowa | W | 31-28 |
| NCAAF | 2022/10/29 19:00 | Indiana State v South Dakota State | W | 7-49 |
| NCAAF | 2022/10/22 20:00 | South Dakota State v North Dakota | W | 49-35 |
| NCAAF | 2022/10/15 19:30 | South Dakota State v North Dakota State | W | 23-21 |
| NCAAF | 2022/10/08 19:00 | South Dakota v South Dakota State | W | 3-28 |
| NCAAF | 2022/10/01 19:00 | Western Illinois v South Dakota State | W | 10-34 |
| NCAAF | 2022/09/24 19:00 | South Dakota State v Missouri St | W | 28-14 |
| NCAAF | 2022/09/17 23:00 | Butler v South Dakota State | W | 17-45 |