[7] Kentucky 19-22 Mississippi [9] 2022-10-01 16:00
Stadium: Vaught-Hemingway Stadium Round: 1
Home Manager: Lane Kiffin Away Manager: Mark Stoops
Head to Head
| NCAAF | 2020/10/03 20:00 | Mississippi v Kentucky | L | 42-41 |
| NCAAF | 2017/11/04 20:00 | Mississippi v Kentucky | L | 37-34 |
| NCAAF | 2011/11/05 12:00 | Kentucky v Mississippi | W | 30-13 |
| NCAAF | 2010/10/02 12:00 | Mississippi v Kentucky | L | 42-35 |
| NCAAF | 2006/09/16 12:00 | Kentucky v Mississippi | W | 31-14 |
| NCAAF | 2005/10/22 12:00 | Mississippi v Kentucky | L | 13-7 |
| NCAAF | 2001/09/29 12:00 | Kentucky v Mississippi | L | 31-42 |
| NCAAF | 2000/09/30 12:00 | Mississippi v Kentucky | L | 35-17 |
Home History
| NCAAF | 2022/09/24 23:00 | Northern Illinois v Kentucky | W | 23-31 |
| NCAAF | 2022/09/17 16:00 | Youngstown State v Kentucky | W | 0-31 |
| NCAAF | 2022/09/10 23:00 | Kentucky v Florida | W | 26-16 |
| NCAAF | 2022/09/03 23:00 | Miami Ohio v Kentucky | W | 13-37 |
| NCAAF Bowl Games | 2022/01/01 18:00 | Kentucky v Iowa | W | 20-17 |
| NCAAF | 2021/11/28 00:30 | Kentucky v Louisville | W | 52-21 |
| NCAAF | 2021/11/20 17:00 | New Mexico State v Kentucky | W | 16-56 |
| NCAAF | 2021/11/14 00:00 | Kentucky v Vanderbilt | W | 34-17 |
Away History
| NCAAF | 2022/09/24 20:00 | Tulsa v Mississippi | W | 27-35 |
| NCAAF | 2022/09/17 19:30 | Mississippi v Georgia Tech | W | 42-0 |
| NCAAF | 2022/09/10 23:00 | Central Arkansas v Mississippi | W | 3-59 |
| NCAAF | 2022/09/03 20:00 | Troy v Mississippi | W | 10-28 |
| NCAAF Bowl Games | 2022/01/02 01:45 | Baylor v Mississippi | L | 21-7 |
| NCAAF | 2021/11/26 00:30 | Mississippi v Mississippi State | W | 31-21 |
| NCAAF | 2021/11/21 00:30 | Vanderbilt v Mississippi | W | 17-31 |
| NCAAF | 2021/11/14 00:00 | Texas A&M v Mississippi | W | 19-29 |