[10] Iowa State 14-20 Oklahoma State [4] 2022-11-12 20:30
Stadium: Boone Pickens Stadium Round: 1
Home Manager: Mike Gundy Away Manager: Matt Campbell
Head to Head
| NCAAF | 2021/10/23 19:30 | Oklahoma State v Iowa State | W | 21-24 |
| NCAAF | 2020/10/24 19:30 | Iowa State v Oklahoma State | L | 21-24 |
| NCAAF | 2019/10/26 19:30 | Oklahoma State v Iowa State | L | 34-27 |
| NCAAF | 2018/10/06 19:30 | Iowa State v Oklahoma State | W | 48-42 |
| NCAAF | 2017/11/11 17:00 | Oklahoma State v Iowa State | L | 49-42 |
| NCAAF | 2016/10/08 19:30 | Iowa State v Oklahoma State | L | 31-38 |
| NCAAF | 2015/11/14 20:30 | Iowa State v Oklahoma State | L | 31-35 |
| NCAAF | 2014/10/04 16:00 | Oklahoma State v Iowa State | L | 37-20 |
Home History
| NCAAF | 2022/11/05 19:30 | West Virginia v Iowa State | W | 14-31 |
| NCAAF | 2022/10/29 16:00 | Oklahoma v Iowa State | L | 27-13 |
| NCAAF | 2022/10/15 16:00 | Iowa State v Texas | L | 21-24 |
| NCAAF | 2022/10/08 23:30 | Kansas State v Iowa State | L | 10-9 |
| NCAAF | 2022/10/01 19:30 | Iowa State v Kansas | L | 11-14 |
| NCAAF | 2022/09/24 16:00 | Baylor v Iowa State | L | 31-24 |
| NCAAF | 2022/09/17 18:00 | Ohio v Iowa State | W | 10-43 |
| NCAAF | 2022/09/10 20:00 | Iowa State v Iowa | W | 10-7 |
Away History
| NCAAF | 2022/11/05 19:30 | Oklahoma State v Kansas | L | 16-37 |
| NCAAF | 2022/10/29 19:30 | Oklahoma State v Kansas State | L | 0-48 |
| NCAAF | 2022/10/22 19:30 | Texas v Oklahoma State | W | 34-41 |
| NCAAF | 2022/10/15 19:30 | Oklahoma State v TCU | L | 40-43 |
| NCAAF | 2022/10/08 19:30 | Texas Tech v Oklahoma State | W | 31-41 |
| NCAAF | 2022/10/01 19:30 | Oklahoma State v Baylor | W | 36-25 |
| NCAAF | 2022/09/17 23:00 | Arkansas Pine Bluff v Oklahoma State | W | 7-63 |
| NCAAF | 2022/09/10 23:30 | Arizona State v Oklahoma State | W | 17-34 |