[5] Guabira 2-1 Real Santa Cruz [12] 2022-09-04 19:00
Stadium: Estadio Ramon Tahuichi Aguilera Round: 15
Head to Head
| Bolivia Apertura | 2022/04/21 22:15 | Guabira v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2022/02/13 19:00 | Real Santa Cruz v Guabira | D | 2-2 |
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | L | 3-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | W | 1-0 |
Home History
| Bolivia Clausura | 2022/08/30 22:00 | The Strongest v Guabira | W | 2-3 |
| Bolivia Clausura | 2022/08/27 19:00 | Atletico Palmaflor Vinto v Guabira | L | 2-0 |
| Bolivia Clausura | 2022/08/24 19:00 | Guabira v Real Tomayapo | W | 2-1 |
| Bolivia Clausura | 2022/08/21 21:15 | Blooming v Guabira | W | 1-3 |
| Bolivia Clausura | 2022/08/13 23:30 | Guabira v Independiente Petrolero | D | 1-1 |
| Bolivia Clausura | 2022/08/11 00:15 | Bolivar v Guabira | L | 3-0 |
| Bolivia Clausura | 2022/08/06 21:15 | Guabira v Royal Pari FC | W | 1-0 |
| Bolivia Clausura | 2022/07/30 21:15 | Universitario De Vinto v Guabira | W | 0-1 |
Away History
| Bolivia Clausura | 2022/09/01 19:00 | Real Santa Cruz v Jorge Wilstermann | D | 0-0 |
| Bolivia Clausura | 2022/08/26 19:00 | Universitario De Vinto v Real Santa Cruz | L | 2-0 |
| Bolivia Clausura | 2022/08/23 19:00 | Real Santa Cruz v Royal Pari FC | W | 2-1 |
| Bolivia Clausura | 2022/08/20 00:15 | Independiente Petrolero v Real Santa Cruz | L | 1-0 |
| Bolivia Clausura | 2022/08/13 19:00 | Real Santa Cruz v Bolivar | L | 1-2 |
| Bolivia Clausura | 2022/08/10 19:00 | Real Santa Cruz v The Strongest | L | 0-3 |
| Bolivia Clausura | 2022/08/05 19:00 | Always Ready v Real Santa Cruz | L | 4-0 |
| Bolivia Clausura | 2022/08/01 19:00 | Real Santa Cruz v Club Aurora | D | 1-1 |