[5] Guabira 2-1 Real Santa Cruz [12] 2022-09-04 19:00
Stadium: Estadio Ramon Tahuichi Aguilera Round: 15
Head to Head
| Bolivia Apertura | 2022/04/21 22:15 | Guabira v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2022/02/13 19:00 | Real Santa Cruz v Guabira | D | 2-2 |
| Bolivia Apertura | 2021/09/27 19:00 | Real Santa Cruz v Guabira | L | 3-0 |
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | W | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | W | 1-0 |