Head to Head
| Uruguay Clausura | 2022/09/11 13:00 | CA River Plate v Defensor Sporting | W | 0-1 |
| Uruguay Torneo Intermedio | 2022/07/21 18:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2022/04/03 00:00 | Defensor Sporting v CA River Plate | W | 3-2 |
| Uruguay Clausura | 2021/02/01 00:30 | Defensor Sporting v CA River Plate | L | 0-2 |
| Uruguay Torneo Intermedio | 2020/11/29 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2020/03/08 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Clausura | 2019/11/16 19:00 | CA River Plate v Defensor Sporting | L | 1-0 |
| Uruguay Torneo Intermedio | 2019/07/27 18:00 | CA River Plate v Defensor Sporting | L | 2-1 |
Home History
| Uruguay Clausura | 2022/09/25 23:30 | Cerrito v Defensor Sporting | W | 1-2 |
| Uruguay Clausura | 2022/09/20 19:00 | Atletico Fenix Montevideo v Defensor Sporting | D | 0-0 |
| Uruguay Clausura | 2022/09/15 23:15 | Defensor Sporting v Cerro Largo | L | 0-1 |
| Uruguay Clausura | 2022/09/11 13:00 | CA River Plate v Defensor Sporting | W | 0-1 |
| Uruguay Cup | 2022/09/07 16:45 | Racing Club de Montevideo v Defensor Sporting | W | 0-1 |
| Uruguay Clausura | 2022/09/03 21:00 | Defensor Sporting v Montevideo Wanderers | W | 1-0 |
| Uruguay Clausura | 2022/08/28 18:00 | Plaza Colonia v Defensor Sporting | W | 0-1 |
| Uruguay Clausura | 2022/08/21 14:15 | Defensor Sporting v Boston River | L | 0-1 |
Away History
| Uruguay Clausura | 2022/09/24 19:00 | Danubio v CA River Plate | L | 3-0 |
| Uruguay Clausura | 2022/09/17 19:00 | CA River Plate v Nacional De Football | D | 1-1 |
| Uruguay Clausura | 2022/09/14 18:30 | Albion FC v CA River Plate | W | 0-2 |
| Uruguay Clausura | 2022/09/11 13:00 | CA River Plate v Defensor Sporting | L | 0-1 |
| Uruguay Clausura | 2022/09/05 16:15 | Cerrito v CA River Plate | W | 1-5 |
| Uruguay Clausura | 2022/08/29 21:00 | Cerro Largo v CA River Plate | W | 0-5 |
| Uruguay Cup | 2022/08/23 23:30 | Juventud de Colonia v CA River Plate | W | 1-2 |
| Uruguay Clausura | 2022/08/20 18:00 | Atletico Fenix Montevideo v CA River Plate | W | 1-2 |