Head to Head
| Uruguay Clausura | 2022/09/11 13:00 | CA River Plate v Defensor Sporting | W | 0-1 |
| Uruguay Torneo Intermedio | 2022/07/21 18:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2022/04/03 00:00 | Defensor Sporting v CA River Plate | W | 3-2 |
| Uruguay Clausura | 2021/02/01 00:30 | Defensor Sporting v CA River Plate | L | 0-2 |
| Uruguay Torneo Intermedio | 2020/11/29 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Apertura | 2020/03/08 20:00 | CA River Plate v Defensor Sporting | D | 1-1 |
| Uruguay Clausura | 2019/11/16 19:00 | CA River Plate v Defensor Sporting | L | 1-0 |
| Uruguay Torneo Intermedio | 2019/07/27 18:00 | CA River Plate v Defensor Sporting | L | 2-1 |
| Uruguay Apertura | 2019/05/11 18:30 | Defensor Sporting v CA River Plate | D | 1-1 |
| Uruguay Clausura | 2018/09/23 19:00 | CA River Plate v Defensor Sporting | L | 3-2 |
| Uruguay Torneo Intermedio | 2018/05/12 18:30 | CA River Plate v Defensor Sporting | L | 1-0 |
| Uruguay Apertura | 2018/04/01 19:00 | Defensor Sporting v CA River Plate | W | 5-2 |
| Uruguay Clausura | 2017/10/14 18:30 | Defensor Sporting v CA River Plate | W | 2-1 |
| Uruguay Apertura | 2017/03/19 19:30 | CA River Plate v Defensor Sporting | W | 0-1 |
| Uruguay Apertura | 2016/09/18 18:30 | CA River Plate v Defensor Sporting | W | 0-5 |
| Uruguay Clausura | 2016/05/29 18:00 | CA River Plate v Defensor Sporting | W | 1-2 |
| Uruguay Apertura | 2015/11/27 23:30 | Defensor Sporting v CA River Plate | L | 1-2 |
| Uruguay Clausura | 2015/05/03 18:30 | CA River Plate v Defensor Sporting | W | 1-2 |
| Uruguay Apertura | 2014/11/01 19:30 | Defensor Sporting v CA River Plate | L | 0-2 |