[17] Mazatlan FC 1-2 Santos Laguna [9] 2023-01-21 03:00
Stadium: Estadio de Mazatlan Round: 3
Referee: Cesar Arturo Ramos Palazuelos Home Manager: Gabriel Caballero Away Manager: Eduardo Fentanes
Head to Head
| Club Friendly List | 2022/12/24 03:00 | Mazatlan FC v Santos Laguna | L | 2-3 |
| Mexico Liga MX | 2022/10/02 23:05 | Santos Laguna v Mazatlan FC | L | 3-0 |
| Mexico Liga MX | 2022/04/20 02:00 | Mazatlan FC v Santos Laguna | W | 1-0 |
| Club Friendly List | 2022/01/29 02:00 | Mazatlan FC v Santos Laguna | W | 2-1 |
| Mexico Liga MX | 2021/10/03 00:06 | Santos Laguna v Mazatlan FC | L | 1-0 |
| Mexico Liga MX | 2021/01/23 03:30 | Mazatlan FC v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2020/11/09 01:06 | Santos Laguna v Mazatlan FC | L | 4-0 |
| Mexico Liga MX | 2016/07/31 23:00 | Santos Laguna v Mazatlan FC | W | 2-4 |
Home History
| Mexico Liga MX | 2023/01/13 03:05 | Atlas v Mazatlan FC | L | 2-1 |
| Club Friendly List | 2022/12/24 03:00 | Mazatlan FC v Santos Laguna | L | 2-3 |
| Club Friendly List | 2022/12/21 03:00 | Atlas v Mazatlan FC | L | 2-1 |
| Club Friendly List | 2022/12/17 03:00 | Chivas Guadalajara v Mazatlan FC | L | 1-0 |
| Club Friendly List | 2022/12/14 03:00 | Tigres UANL v Mazatlan FC | D | 0-0 |
| Mexico Liga MX | 2022/10/02 23:05 | Santos Laguna v Mazatlan FC | L | 3-0 |
| Mexico Liga MX | 2022/09/24 00:00 | Necaxa v Mazatlan FC | D | 2-2 |
| Mexico Liga MX | 2022/09/17 02:00 | Mazatlan FC v Toluca | D | 1-1 |
Away History
| Mexico Liga MX | 2023/01/15 03:05 | Santos Laguna v Unam Pumas | W | 3-0 |
| Mexico Liga MX | 2023/01/09 01:00 | Santos Laguna v Tigres UANL | L | 0-3 |
| Club Friendly List | 2022/12/27 23:00 | Tigres UANL v Santos Laguna | D | 1-1 |
| Club Friendly List | 2022/12/24 03:00 | Mazatlan FC v Santos Laguna | W | 2-3 |
| Club Friendly List | 2022/12/20 03:00 | Chivas Guadalajara v Santos Laguna | L | 4-0 |
| Club Friendly List | 2022/12/13 03:00 | Atlas v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2022/10/17 00:06 | Santos Laguna v Toluca | L | 1-2 |
| Mexico Liga MX | 2022/10/14 00:06 | Toluca v Santos Laguna | L | 4-3 |